The Pfizer Rare Disease Research Unit is seeking a Postdoctoral Fellow to lead a project on the role of non-coding RNA in neurobiology and neurological disease. The scope of this project will leverage state of the art technology, collaboration with internal experts, and drive future directions of therapeutic development. This opportunity will provide the Postdoctoral Fellow a highly visible research project with impact both internally in Pfizer, and broadly through publication.
Pfizer Rare Disease merges pioneering science with a deep understanding of the underlying disease pathology to deliver innovative treatments. With over three decades of experience in rare disease, our broad global rare disease portfolio aims to address the unmet medical needs across a number of therapeutic areas, including hematology, neurology, endocrinology, cardiology, and inherited metabolic diseases.ROLE RESPONSIBILITIES
- Conduct independent research in non-coding RNA biology, perform experiments, analyze data, and describe findings at internal and external events and in submitted publications
- Proactively identify new research directions and testable hypotheses, taking full advantage of Pfizer internal knowledge and resources.
- Contribute intellectually to the wider group of the Pfizer Rare Disease Research Unit
- Recent PhD in molecular biology, cell biology, genetics, or related discipline with a minimum of 1 high quality first-author publication(s) is required.
- An in-depth understanding of RNA biology
- Significant molecular biology experience including expertise in cell culture technique, immortalized cell lines and iPSCs, molecular cloning, in vitro knockdown strategies (CRISPR, siRNA), and quantitative PCR.
- Experience generating and analyzing RNA sequencing data, including single cell
- Technical expertise in non-coding RNA biology
- Experience working with human iPSC derived neurons
OTHER JOB DETAILS
- Use of Personal Protective Equipment (PPE) in a BSL-2 laboratory
- Standard business office conditions.
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Research and Development