Research associate position in Personalized breast cancer treatment and functional drug testing
- Employer
- University of Basel
- Location
- Basel, Switzerland
- Closing date
- Jun 19, 2022
View more
- Sector
- Pharmaceutical, Business Development
- Hours
- Full Time
- Organization Type
- University and College
- Jobseeker Type
- Academic (e.g. 'Lecturer')
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A research associate position is available in the laboratory of Professor Momo Bentires-Alj ( https://bentireslab.org/ ) at the Department of Biomedicine (DBM) in Basel, Switzerland. The successful candidate will work on breast cancer organoid culture and image-based drug screening.
Selected publications of our lab include: 1- PIK3CA H1047R induces multipotency and multi-lineage mammary tumors. Koren S, et al., Nature 2015. 2- Hippo kinases LATS1/2 control human breast cell fate via crosstalk with ERα. Britschgi A, et al., Nature 2017. 3. Glucocorticoids promote breast cancer metastasis. Obradović MMS, et al. Nature 2019. 4. Hepatic stellate cells suppress NK cell sustained breast cancer dormancy. Correia AL, et al., Nature 2021.
Your position
The tasks include: a) Manage and characterize breast cancer patient-derived organoid samples, b) Assess their response to therapy using image-based drug screening (Pharmacoscopy); and c) support researchers with projects that involve such samples.
Your profile
A strong experience in primary 3D cell culture and imaging. A background in cell biology, molecular biology, immunology or related discipline. Expertise in drug screening, lentivirus and/or CRISPR systems and/or mouse work is a plus. The candidate should be well-organized, highly motivated, have strong collaboration and team working skills. Good communication skills fluency in English are required.
We offer you
A stimulating, challenging and interdisciplinary translational research environment, state-of-the-art technologies and core facilities, and attractive employment conditions. The DBM is an international institute pursuing basic, translational and clinical research, with access to cutting-edge core facilities.
Lab website: https://bentireslab.org/ .
Selected publications of our lab include: 1- PIK3CA H1047R induces multipotency and multi-lineage mammary tumors. Koren S, et al., Nature 2015. 2- Hippo kinases LATS1/2 control human breast cell fate via crosstalk with ERα. Britschgi A, et al., Nature 2017. 3. Glucocorticoids promote breast cancer metastasis. Obradović MMS, et al. Nature 2019. 4. Hepatic stellate cells suppress NK cell sustained breast cancer dormancy. Correia AL, et al., Nature 2021.
Your position
The tasks include: a) Manage and characterize breast cancer patient-derived organoid samples, b) Assess their response to therapy using image-based drug screening (Pharmacoscopy); and c) support researchers with projects that involve such samples.
Your profile
A strong experience in primary 3D cell culture and imaging. A background in cell biology, molecular biology, immunology or related discipline. Expertise in drug screening, lentivirus and/or CRISPR systems and/or mouse work is a plus. The candidate should be well-organized, highly motivated, have strong collaboration and team working skills. Good communication skills fluency in English are required.
We offer you
A stimulating, challenging and interdisciplinary translational research environment, state-of-the-art technologies and core facilities, and attractive employment conditions. The DBM is an international institute pursuing basic, translational and clinical research, with access to cutting-edge core facilities.
Lab website: https://bentireslab.org/ .
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