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Associate Scientist - Immuno-oncology

Employer
Gilead Sciences
Location
Belmont, CA
Closing date
Jun 23, 2022

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Sector
Science, Doctors, Oncology and Radiotherapy
Organization Type
Corporate
The Research Oncology department at Gilead Sciences (Foster City, CA) is seeking an exceptional Associate Scientist to join our Immuno-oncology group. Gilead is a world leader in antiviral research having developed small molecule compounds that have revolutionized the treatment of HIV, HCV, and HBV. Over the last 5 plus years, Gilead has significantly broadened its scope to encompass unmet medical needs in cancer and inflammation. Our research team is engaged in the discovery and development of novel therapeutics targeting the tumor microenvironment, with the goal of potentiating the anti-tumor immune response and synergizing with established and emerging immunotherapy approaches. The successful candidate will integrate into this team, leading and supporting biological investigation of new and established therapeutic targets. This position provides an exciting opportunity to have high-impact participation in the growth of a new research area within the established and highly collaborative oncology research group at Gilead.

Essential Duties and Job Responsibilities:
  • Drive discovery and translational research aimed at identifying and advancing novel therapeutics.
  • Design and execute rigorous, hypothesis-based experiments; analyze and interpret data to support initiation and/or advancement of therapeutic programs.
  • Engage in cross-functional collaborations across Gilead's research organization (e.g. Medicinal Chemistry, Protein Therapeutics, High-Throughput Biology, Bioinformatics, Clinical Oncology, Biomarkers) to effectively develop new drugs.
  • May participate in evaluation of external licensing opportunities.
  • Participate as an engaged member of the highly interactive Oncology department. Present research findings and recommendations to senior staff and contribute to preparation of research reports, manuscripts, INDs, and patent filings.

Knowledge, Experience and Skills:
  • BS 5+ years or MS 3+ years or equivalent degree of relevant experience, preferably in drug development.
  • Strong background in immunology and flow-cytometry-based assay development and experience running functional immune cell activation assays is desired.
  • Fluency in the use of molecular techniques to evaluate signaling networks and cellular phenotypes (e.g., western blot, ELISA, proteomics as well as siRNA/shRNA, CRISPR and gene expression analysis).
  • Experience with primary immune cell culture and engineering (human and murine models), functional genomics platforms (CRISPR, lentiviral/retroviral cell engineering; arrayed or pooled phenotypic screens) is highly desired.
  • A working knowledge of the design and execution of in vivo animal model studies is a plus.
  • Strong communication skills required, with an ability to communicate and scientifically engage individuals across a large breadth of levels and translate ideas and data into concise written and verbal communications.

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