Sr Research Scientist I, Tumor Microenvironment - Oncology

We are seeking an exceptional immunologist to join the Oncology department at Gilead Sciences, Inc. Our research team is engaged in the discovery and development of novel therapeutics targeting the stromal and myeloid compartments, with the goal of potentiating the anti-tumor immune response and synergizing with established and emerging immunotherapy approaches. The successful candidate will integrate into this team, leading and supporting biological investigation of new and established therapeutic targets. This position provides an exciting opportunity to have high-impact participation in the growth of a new research area within the established and highly collaborative oncology research group at Gilead.

Essential Duties and Job Responsibilities:

• Drive discovery and translational research aimed at identifying and advancing novel therapeutics.
• Identify key scientific questions, design hypothesis-based experiments and analyze and interpret data to support initiation and/or advancement of therapeutic programs.
• Engage in cross-functional collaborations across Gilead's research organization (e.g. Medicinal Chemistry, Protein Therapeutics, High-Throughput Biology, Bioinformatics, Clinical Oncology, Biomarkers) to effectively develop new drugs.
• Participate in established external collaborations and bring outside expertise to Gilead by identifying and engaging new academic collaborators.
• Participate in evaluation of external licensing opportunities.
• Participate as an engaged member of the highly interactive Oncology department.
• Present research findings and recommendations to senior staff and contribute to preparation of research reports, manuscripts, INDs, and patent filings.
• Manage Research Associates or direct members of project teams in the initiation and execution of laboratory experimentation.

Knowledge, Experience and Skills:

• PhD or equivalent degree and 6+ years of relevant post-graduate experience, with a track record of experience in drug development.
• Strong background in immunology, with expertise in myeloid cell biology a plus.
• Experience with flow-cytometry-based assay development and running functional immune cell activation assays is desired.
• Fluency in the use of molecular techniques to evaluate signaling networks and cytokine/chemokine expression (eg. western blot, ELISA, proteomics as well as siRNA/shRNA, CRISPR and gene expression analysis).
• A working knowledge of the design and execution of in vivo animal model studies and experience working with third party CROs to implement animal studies is desired.
• Strong communication skills required, with an ability to communicate and translate ideas and data into concise written and verbal communications.