Research Associate II, Bioanalytics-TDI

Position Summary

Supports antibody and biologics lead discovery and optimization efforts across the Biologics portfolio through protein characterization by analytical and biophysical methods. This role actively contributes to creating a collaborative, productive and scientifically rigorous working environment and works closely with teams across the Biologics group and its academic collaborators.

Job Responsibilities

• Performs therapeutic antibody characterization using various UPLC and HPLC techniques, such as ion exchange (IEX), size exclusion (SEC), hydrophobic interaction (HIC), reverse phase (RP).
• Analyzes size and charge variants by capillary electrophoresis sodium dodecyl sulfate (CE-SDS) and capillary isoelectric focusing (CIEF).
• Performs light scattering analysis by SEC-MALS and DLS.
• Responsible for intact mass analysis and peptide mapping by mass spectrometry.
• Performs protein concentration determination (UV).
• Writes and reviews formal reports, including method protocols and other technical documents.
• Performs other related duties as assigned.

Education

• Bachelor's Degree

Experience

BS/MS in Chemistry or Biochemistry.

2-5 years laboratory experience in analytical chemistry, protein chemistry, or

biochemistry in an academic laboratory, or in the pharmaceutical or

biotechnology industry.

A highly motivated scientist with an understanding of the fundamentals of protein chromatography and hands-on experience with analytical tools and sample preparation.

Proven track record and understanding of general chromatography and spectroscopy principles.

Experience in electrophoresis and capillary electrophoresis.

Experience with protein purification is preferred.

Proficiency with enzyme-linked immunosorbent assay (ELISA) and Western Blot.

Knowledge, Skills and Abilities

• Attention to detail and multitasking abilities, with the ability to work both independently and as part of a team
• Motivation to learn and grow in scientific expertise.
• Ability to trouble-shoot technical issues.
• Strong communication and presentation skills.
• Ability to work on multiple projects simultaneously.

Licenses and Certifications

Working Conditions/Physical Demands

Weill Cornell Medicine is a comprehensive academic medical center that's committed to excellence in patient care, scientific discovery, and the education of future physicians in New York City and around the world. Our doctors and scientists-faculty from Weill Cornell Medical College, Weill Cornell Graduate School of Medical Sciences, and the Weill Cornell Physician Organization-are engaged in world-class clinical care and cutting-edge research that connect patients to the latest treatment innovations and prevention strategies. Located in the heart of the Upper East Side's scientific corridor, Weill Cornell Medicine's powerful network of collaborators extends to its parent university Cornell University; to Qatar, where an international campus offers a U.S. medical degree; and to programs in Tanzania, Haiti, Brazil, Austria and Turkey. Our medical practices serve communities throughout New York City, and our faculty provide comprehensive care at NewYork-Presbyterian Hospital/Weill Cornell Medical Center, NewYork-Presbyterian/Lower Manhattan Hospital, and NewYork-Presbyterian/Queens. At Weill Cornell Medicine, we work together to treat each individual, not just their conditions or illnesses, as we strive to deliver the finest possible care for our patients - the center of everything we do. Weill Cornell Medicine is an Equal Employment Opportunity Employer. Weill Cornell Medicine provides equal employment opportunities to all qualified applicants without regard to race, sex, sexual orientation, gender identity, national origin, color, age, religion, protected veteran or disability status, or genetic information.