Research Scientist, Immuno-oncology

The Research Oncology department at Gilead Sciences (Foster City, CA) is seeking a talented and highly motivated Research Scientist to join our Immuno-oncology group. Our collaborative and interdisciplinary research team utilizes state-of-the-art technologies and innovative methodologies to advance medicines into the clinic. The successful candidate is expected to contribute to the discovery, research, and development of novel immunotherapeutic agents to address unmet medical needs of cancer patients. S/he will have opportunities for career growth through acquisition of new skills, experiences, and professional relationships in a fast-paced and resource-rich environment.

Key Responsibilities

• Independently plan, design, execute, analyze, and interpret key in vitro and in vivo proof of concept studies to support novel I/O drug development efforts
• Develop and validate efficient molecular and cell-based screening assays to critically evaluate novel agents
• Proactively evaluate new technologies and develop new assays to support early-stage discovery activities and build strong internal scientific expertise
• Manage multiple projects simultaneously and work cross-functionally with colleagues in the oncology, virology, protein engineering, chemistry, translational medicine, biomarker and clinical groups
• Present research findings and recommendations to senior staff and contribute to preparation of research reports, manuscripts, INDs, and patent filings
• May manage Research Associates or direct members of project teams in the initiation and execution of laboratory experimentation

Knowledge, Experience and Skills

Required:

• PhD degree in immunology, cancer immunotherapy, cancer biology or cell biology
• Minimum of 2 years post-doctoral experience focused on innovative research in immunology with proven achievements in industrial or academic settings
• Expertise in cellular immunology of innate (macrophage, DC, neutrophil) and/or adaptive (T, NK) cell systems
• Direct experience in molecular and cell biology techniques investigating immune cell function
• Attention to detail with excellent organizational and record keeping skills
• Strong motivation, independence and ability to think critically and creatively to resolve problems
• Excellent communication and interpersonal skills and ability to integrate into a high-paced multidisciplinary environment

Desirable:

• Expertise in signaling mechanisms of checkpoints and/or innate immunosuppression
• Experience with cell engineering (e.g. CRISPR, lenti/retro-viral systems) of immune cells
• Direct experience in research drug discovery in immuno-oncology
• Experience with the study design/execution of in vivo tumor models