Process Development Scientist - Upstream

Position Description:
Company Overview: Jecho Laboratories, Inc. (Jecho) is a biopharmaceutical company developing innovative therapeutic biologics, including therapeutic monoclonal antibodies, cytokines, immunotoxins, and vaccines to address a broad range of infectious diseases as well as treatment of cancer. The company headquarter is in Frederick Maryland, USA.
We are seeking a Process Development Scientist to join our R&D team in Frederick, MD. Qualified individuals will play an important role in upstream process development for biotherapeutics. The candidate must work independently on experiment design, data analysis, summary and report. The candidate is expected to be well organized, multi-functional and self-motivated.
Responsibilities:

• Independently design and conduct experiments for upstream process development (cell line development, cell culture condition development and optimization, cell line characterization, etc.) with sound scientific rationales.
• Perform PD studies from transient and stable transfection to benchtop bioreactor, as well as the associated assays and analyses.
• Generate, evaluate, and maintain critical data in a highly organized manner.
• Write scientific proposals, protocols, progress reports, and scientific papers.
• Train, coordinate, and supervise PD junior staff.
• Collaborate and coordinate with Discovery, PD Downstream, and Analytical Development groups.
• Assist tech transfer activities such as providing operation parameters, writing technical reports, and performing tech transfer.

Qualifications:
Minimum Requirements:

• Ph.D. in biological science, biotech/bioengineering, or other related areas. 1-2 years experience in the pharmaceutical or biotechnology field. Or Master with a minimum of 5 years of experience.
• Extensive hands-on experience in antibody and/or recombinant protein expression in mammalian cells, cell culture, clone generation, process development, and scale-up.
• Working knowledge with cell culture bioreactors.
• Diverse knowledge and experience in various relevant areas, including but not limited to molecular/cell biology, biochemistry, neuroscience, immunology, and others.
• Capable of performing multiple functions in a fast-paced environment.
• Strong technical writing and good presentation skills.
• Excellent record-keeping abilities to support drug development and IND filing.
• Understanding of FDA regulatory requirements related to biologicals approval for human use.