Scientist, NGS

Commonwealth Sciences, Inc.
Boston, MA
Closing date
Jun 28, 2022

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Organization Type
Position located in Cambridge, MA.

Responsibilities of the Scientist, NGS:
  • Develop, design, optimize and execute assays to assess the genome-modifying potential of base editors.
  • Support off-target editing risk assessment for different projects.
  • Next-generation sequencing (NGS) library preparation and sequencing.
  • Mammalian cell culture and transfection.
  • Maintain detailed documentation of experiments in the ELN system.
  • Coordinate and work with other teams at Beam in a highly matrixed environment.
  • Data analysis to visualize outcomes of genome editing.

Requirements of the Scientist, NGS:
  • PhD in cell biology, molecular biology, genetics or other relevant field or Bachelors/Masters degree with 10 years relevant experience.
  • Industry experience is preferred.
  • Demonstrated mastery of NGS including DNA/RNA sequencing library preparation and quantification, familiarity with Illumina sequencing platforms e.g. Miseq, and extensive experience in molecular biology and cell biology (DNA/RNA extraction, PCR, qPCR, ddPCR, cell culture and transfection).

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