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Research Assistant- Neural Plasticity

Lieber Institute Inc
Baltimore County, MD
Closing date
Jun 26, 2022

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Lieber Institute Inc


A little about us:

The Lieber Institute for Brain Development (LIBD) was established in 2010 to plot a new course in biomedical research that would change the lives of individuals affected with developmental brain disorders. We are one of the only research institutions in the world focused specifically on understanding how genes and the environment influence the way our brains develop that lead to conditions such as schizophrenia, autism, bipolar disorder and related developmental brain disorders. Through our cutting-edge research, answers are emerging and being translated into a robust pipeline of new drugs in development. And, by focusing on genes and their dynamic interplay with the environment, we are getting even closer to the holy grail in medical research, the discovery of strategies for primary prevention.

We are a group of dedicated, multidisciplinary and optimistic researchers, working at the cutting edge of science, utilizing state-of-the-art tools to unlock the mystery of the brain and transform the way we approach the development of new treatments, and ultimately cures. LIBD is an independent 501(c)(3) medical research institute located in the Bioscience Park on the campus of the Johns Hopkins School of Medicine and Hospital in Baltimore, MD.

Job Summary:

We are seeking a self-motivated individual to join our research group as a Research Assistant. This research assistant position is open to recent college graduates seeking training and experience in a translational research setting that are planning to pursue a graduate or professional degree in science or medicine. The candidate will gain experience in a translational research setting with a focus on spatial transcriptomics projects in postmortem human brain tissue in a dynamic team-based environment. Projects aim to generate transcriptome-scale maps in the human brain to understand differences in spatial gene expression in neuropsychiatric disorders. Candidates should have a bachelor's degree in neuroscience, cellular, or molecular biology. Familiarity or research experience with molecular/cellular biology, confocal microscopy, FACS sorting, and/or next generation sequencing would be helpful, but not required. The position requires ability to participate in experimental design, conduct experiments and work with computational biologists to analyze data. Initiative to learn new methods and perform work efficiently and carefully are essential.

Overview of Duties:

· RNA extraction and qPCR

· RNA-seq library construction

· Nuclei isolation and FACs sorting

· Immunohistochemistry

· Confocal imaging and slide-scanning

· Assist with brain tissue dissections

Cryosectioning, histological or immunofluorescence staining, confocal microscopy

Minimum Qualifications:

· BA or BS in Neuroscience, Cell Biology, or a closely related field

· Molecular biology experience

· Excellent organizational and communication skills

· Flexible work schedule

Special Knowledge, Skills, and Abilities:

Familiarity with any of the following topics or techniques is a plus:

· Programming in MATLAB, R or Python

· Flow cytometry

· Next generation sequencing

· Neuroanatomy

Physical Requirements:

- Remaining in a seated or standing position for extended periods of time;

- Reaching and grasping to manipulate objects with fingers;

- Mobility, including the ability to maneuver around a laboratory setting including the ability to move materials weighing up to 25 pounds;

- Communication skills using the spoken and written word;

- Having the ability to receive detailed information through oral communication;

- All other physical demands in a standard laboratory environment.


** If accommodations are needed due to pregnancy or a disability, please contact

EEOC Statement:

The Lieber Institute for Brain Development is proudly an equal employment opportunity and equal professional advancement employer. Employment decisions at the Lieber Institute for Brain Development are based on merit, qualifications, and abilities. It is our policy that the Lieber Institute does not discriminate in employment opportunities on the basis of race, religion, color, sex, age, marital status, national origin or ancestry, citizenship, physical or mental disability, sexual preference/orientation or veteran status with regard to any position or employment for which the applicant or employee is qualified.

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