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Senior Data Scientist - Cheminformatics

Cambridge, Massachusetts
Closing date
Aug 12, 2022

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Science, Mathematics and Statistics, Pharmaceutical
Full Time
Organization Type
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The Computational Pharmacology Group in the Medicine Design Department at Pfizer is seeking a highly motivated Senior Data Scientist to design and implement cheminformatics approaches and workflows to help accelerate our drug discovery process. The successful candidate will play a pivotal role in unlocking the underlying value of Pfizer's proprietary pharmacology and other related data. The ideal candidate will develop and deploy data analytics tools and workflows that support the decision-making process of drug designers on projects across all of Pfizer's therapeutic areas. The candidate will also support the design and implementation of data pipelines to organize and integrate internal and external pharmacology and associated data. The scientist will have the opportunity to make an impact directly on specific projects through clear communication of actionable insights with data-driven analyses. The candidate will also be encouraged to present their work internally and at conferences and publish in peer-reviewed journals. With strong communication skills and adept at building productive partnerships, the successful candidate will thrive working in cross-functional teams with talented scientists across different disciplines. The ability to think innovatively, manage complex technical challenges, strong attention to detail, and a drive to problem solving will make this role a success.

  • Mine pharmacology and related data from variety of internal corporate databases and external providers
  • Organize data and integrate into cheminformatics-related databases enabled for efficient data analytics
  • Design, develop and deploy general purpose data pipelines and data analytics tools and workflows
  • Analyze large-scale and complex data sets for actionable insights to enable project teams with decision making
  • Generate computational predictive models from pharmacology and related data to support drug design
  • Communicate results both internally and externally via presentations and publications
  • Establish scientific and technical expertise through familiarity with scientific literature and attending conferences


Basic Qualifications
  • PhD in cheminformatics, computer science, AI/ML or a related discipline
  • 5+ years of relevant research experience, preferably in the biotech or pharmaceutical industry or equivalent field
  • Demonstrated experience in developing and implementing data analytics solutions
  • Proficient in in scripting and high level programming languages (e.g. R, Python, Java)
  • Experience with cheminformatics toolkits (e.g. RDKit) and data analytics platforms (e.g. Pipeline Pilot, Knime)
  • Excellent track record of external publications and professional service
  • Outstanding outreach, teamwork, and communication skills

Preferred Qualifications
  • Experience developing statistical and machine learning models
  • Knowledge of data visualization tools (e.g. Spotfire)
  • Familiar with cloud computing platforms and handling SQL/NoSQL databases


Sitting, standing, lifting, bending, and walking. Ability to work on a computer (while standing or sitting). Ability to perform mathematical calculations and interpret data.


Candidate will be asked to occasionally travel to the Pfizer site in Groton, CT to meet colleagues from other departments.

Additional Job Information
  • Relocation Support Available
  • Eligible for employee referral bonus


Pfizer requires all U.S. new hires to be fully vaccinated for COVID-19 prior to the first date of employment. As required by applicable law, Pfizer will consider requests for Reasonable Accommodations.

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Research and Development
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