Senior Associate Scientist, Metabolism (non-PhD)

Why Patients Need You

Pfizer's purpose is to deliver breakthroughs that change patients' lives. Research and Development is at the heart of fulfilling Pfizer's purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best in class medicines to patients around the world.

What You Will Achieve

Obesity is a growing health and economic burden worldwide. It is risk factor for other co-morbidities including heart disease, stroke, Type 2 Diabetes Mellitus (T2DM), certain types of cancer, and higher mortality risk from COVID-19 infection. The Internal Medicine Research Unit (IMRU) is seeking a highly motivated non-PhD (Bachelor's or Master's level) scientist with rodent handling and cell culture experience to support preclinical drug discovery efforts around obesity. The ideal candidate will be able to design and execute both in vivo and in vitro experiments, as well as analyze, interpret, and effectively communicate results. The candidate will work closely with manager and other IMRU Pfizer scientists to support exploratory and portfolio efforts.

How You Will Achieve It

• Plan, design and execute in vivo experiments. Comfortable handling and dosing (IP, SC, PO and IV) rodents. Blood and tissue collection.
• Perform cell culture experiments.
• Conduct molecular biology experiments such as but not limited to transfection, gene expression analysis, immunostaining, ELISA and Western blotting.
• Capable of following assay protocols and analyzing and interpreting data.
• Compliance to laboratory safety and electronic notebook standards.
• Work effectively with peers to support projects.
• Identify and report any experimental problems, proactively troubleshoot causative factors, and implement necessary corrections following discussion with supervisor.

Qualifications

Must-Have

• Bachelor's or Master's degree in biology, pharmacology, biochemistry, molecular biology or other related discipline
• At least 3 years of lab experience in academia or in industry for Bachelor's.
• Hands-on rodent handling, dosing, and tissue collection experience.
• Familiarity with standard cell and molecular biology methods including but not limited to cell culture, siRNA and plasmid transfections, immunoassays such as ELISAs and western blotting, and quantitative real-time PCR.
• Ability to use appropriate software to perform data analysis.
• Excellent organization and planning skills, the ability to work in a fast-paced environment independently or as part of a team, strong motivation with a dedicated work ethic.
• Excellent verbal and written communication skills.
• Creative, self-motivated and the ability to work independently including analysis and troubleshooting of experimental results and reviewing literature to formulate new approaches.

Nice-to-Have

• Bachelors' degree with 4+ years of experience or Master's degree and 2+ years of relevant experience.
• Experience with rodent handling and dosing (IP, SC, PO and IV).
• Knowledge of metabolism and pharmacology.
• Experience working in or collaborating with industry.

Other Job Details

• Eligible for Relocation Support

#LI-PFE

Pfizer requires all U.S. new hires to be fully vaccinated for COVID-19 prior to the first date of employment. As required by applicable law, Pfizer will consider requests for Reasonable Accommodations.

Sunshine Act

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EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Research and Development