Research Associate

*Department:*SOP-CICBDD - 452101
*Posting Open Date:*07/18/2022
*Open Until Filled:*Yes
*Position Type:*Postdoctoral Scholar
*Position Title:*Postdoctoral Research Associate (Synthetic Chemistry-Heterocycles)
*Vacancy ID:*PDS003539
*Full-time/Part-time:*Full-Time Temporary
*Hours per week:*40
*FTE:*1
*Work Location:*Chapel Hill, NC
*Position Location:*North Carolina, US
*Hiring Range:*Dependent on experience and qualifications.
*Proposed Start Date:*08/29/2022
*Estimated Duration of Appointment:*12 Months
*Primary Purpose of Organizational Unit:*The UNC Eshelman School of Pharmacy (www.pharmacy.unc.edu) is one of five health science schools (Pharmacy, Nursing, Dentistry, Public Health, Medicine) at the University of North Carolina at Chapel Hill and is one of the oldest health science academic programs at Chapel Hill. The School teaches approximately 600 PharmD students and 145 graduate students. The School has built a reputation for its continued pursuit of excellence, rigorous education and training programs, cutting-edge multidisciplinary research, progressive pharmacy practices, efficient business operations, and its outstanding faculty, staff, and students. The School was named the number one School of Pharmacy in the U.S. by the U.S. News and World Report. The School has experienced unprecedented growth and success and continues to strategically position itself for sustained impact, as articulated in the School s Strategic Plan (
Our Vision is to be the global leader in pharmacy and pharmaceutical sciences. Our Mission is to prepare leaders and innovators to solve the world s most pressing health care challenges. We are Advancing Medicine for Life through innovation and collaboration in pharmacy practice, education, research, and public service.
*Position Summary:*Synthetic organic chemist position focused on the design and construction of novel molecules for one of two distinct projects: (1) selective dopamine modulation, or (2) anti-metastasis therapeutic development. The postdoctoral scholar for each project will be responsible for the design and construction of novel heterocyclic compounds possessing improved potency and selectivity. For each project we will partner with leading external researchers to facilitate the interrogation of the compound s biological activity. Thus, this position is dedicated to the development of new synthetic methods and routes to the target scaffolds and their application to construct optimized analogues. Research is conducted within the highly collaborative environment of the UNC Center for Integrative Chemical Biology and Drug Discovery.
*Minimum Education and Experience Requirements:*PhD. in organic chemistry, medicinal chemistry or related discipline
*Required Qualifications, Competencies, and Experience:*- Strong organic synthesis skills, as evidenced by peer reviewed publications.
- Experience with a wide range of purification techniques (e.g. flash chromatography, HPLC, distillation, etc.)
- Evidence of collaborative research experience.
- Experience in the construction of heterocyclic molecules.- Extensive familiarity with NMR acquisition and spectral analysis.
*Preferred Qualifications, Competencies, and Experience:*See Required Qualifications, Competence and Experience.
*Special Physical/Mental Requirements :*Must comply with all environmental health and safety rules including proper use of all personal protective equipment
*Special Instructions:*Apply online at, [ with a cover letter, CV/resume, research statement and a list of at least 3 professional references with their full contact information.
The School s vision is grounded in our aspiration to be a diverse and inclusive community of people who accelerate new thinking and ideas in education, research, and practice that have a positive impact on human health worldwide. We envision a school that reflects, in all its dimensions, the population it serves.
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Associated topics: chemical, chemical engineering, coatings, nutrition, pha, phenolic, polymer, polymer synthesis, polypropylene, polyurethane