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Research Fellow in KSHV Biology

Employer
University of Leeds
Location
Leeds, United Kingdom
Salary
£35,333 to £42,155 p.a.
Closing date
Sep 23, 2022

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Sector
Science, Life Sciences, Cell and Molecular Biology
Hours
Full Time
Organization Type
University and College
Jobseeker Type
Academic (e.g. 'Lecturer')
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Are you an early career researcher looking for your first challenge?

Do you have a background in Molecular virology and RNA biology. Do you want to further your career in one of the UK's leading research intensive Universities?

Project Title: Kaposi's sarcoma-associated herpesvirus manipulation of host cell non-coding RNA networks and RNA modification pathways.

The Whitehouse research group is seeking a highly motivated Research Fellow to investigate how the human tumour virus, Kaposi's sarcoma-associated herpesvirus (KSHV), manipulates host cell non-coding RNA networks and RNA modification pathways to enhance its own replication. The project will use a range of molecular and cell biology approaches to highlight a novel KSHV-mediated mechanism to regulate viral gene expression. Moreover, this project aims to identify a novel targets for antiviral intervention for this important human tumour virus.

The successful candidate will become part of a multi-member laboratory team investigating the molecular mechanisms of viral infection and the essential role of virus-host cell events. These are fundamentally important to ultimately develop new effective antiviral agents that target viral proteins or host factors.

For this role, you should have a PhD (or close to completion) in molecular virology or a closely allied discipline. You should also have experience in growth, analysis and manipulation of Kaposi's sarcoma-associated herpesvirus, as well as in virus-mediated manipulation of ncRNA networks and RNA modification pathways. Experience in a wide range of RNA-based techniques, qRT-PCR, protein production, mammalian cell culture, immunoblotting, and lentivirus-shRNA depletion approaches in B cells is also essential.

The University of Leeds and the Faculty of Biological Sciences are committed to providing equal opportunities for all and offer a range of family friendly policies. The University is a charter member of Athena SWAN (the national body that promotes gender equality in higher education), and the Faculty of Biological Sciences was awarded a Silver award in 2020. We are proud to be an inclusive Faculty that values all staff, and are happy to consider job share applications and requests for flexible working arrangements from our employees. Our Athena SWAN webpage provides more information.

To explore the post further or for any queries you may have, please contact:

Professor Ade Whitehouse , Professor of Molecular Virology

Tel: +44 (0)113 343 7096 | Email: a.whitehouse@leeds.ac.uk
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