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Senior Associate Scientist, BioProPuriRecv

Employer
Pfizer
Location
Andover, Massachusetts
Salary
Competitive
Closing date
Sep 29, 2022

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Sector
Science, Pharmaceutical
Hours
Part Time
Organization Type
Corporate
Jobseeker Type
Professional
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Why Patients Need You

Pfizer's purpose is to deliver breakthroughs that change patients' lives. Research and Development is at the heart of fulfilling Pfizer's purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best - in - class medicines to patients around the world.

What You Will Achieve

All over the world, Pfizer colleagues work together to positively impact health for everyone, everywhere. In your role, you'll work as a part of Pfizer Vaccine Research and Development, which seeks to discover novel vaccines (prophylactic and therapeutic) for the prevention and treatment of significant human diseases (e.g. infectious diseases, oncology) using a variety of vaccine technology platforms combined with immunomodulatory agents.

As a Senior Associate scientist, you will be at the center of our operations and you'll find that everything we do, every day, is in line with an unwavering commitment to quality. Your significant experience of applying knowledge of principles, concepts, and practices of the discipline will make you a critical member of the team. Your skill and knowledge will help in making decisions that require choosing among limited options. You are proactive in contributing to all team discussions and creating an environment of collaboration.

It is your hard work and dedication that will make Pfizer ready to achieve new milestones and help patients across the globe.

How You Will Achieve It
  • Apply technical skills to projects/ assignments within own work group/ project team.
  • Conduct experimental design in consultation with supervisor, literature review and increasing emphasis on independent design based on experience.
  • D evelop and test new hypotheses to improve the fundamental understanding of recovery and purification processes.
  • Execute operational efficiency improvements and planning and implementing improvements across Bioprocess R&D work processes.
  • Carry out on-going analysis of data generated and will identify problems.
  • Implement necessary changes following discussion with peers/supervisor.
  • Analyze and interpret experimental data, results and methodology used with guidance.
  • Present problems and propose solutions in discussions with group members.
  • Independently analyze, interpret, and provide conclusion and present experimental data.
  • Plan and prioritize related recovery/purification activities.


POSITION SUMMARY
The purpose of the Senior Associate Scientist position is to provide the planning and execution of
experiments designed to aid in defining manufacturing processes for biopharmaceuticals. The successful candidate will have a working knowledge of biochemistry, and related analytical chemistries,
chromatography, centrifugation, precipitation, and filtration design principles. This position requires the design and execution of experiments using these technologies and the ability to evaluate and clearly reporting the results to laboratory colleagues and other affected functional areas.

POSITION RESPONSIBILITIES
The successful Senior Associate Scientist applicant will have experience in laboratory research, and a desire to continue in a laboratory-focused role. This position will join a larger team of scientists across multiple sites focused on developing and optimizing recovery and purification processes for recombinant proteins and biological macromolecules for early- and late-phase clinical trials. The Senior Associate Scientist will be responsible for working with fellow scientists to develop robust, efficient, scalable strategies for improving process performance. Responsibilities will include small-scale studies, and pilot plant and manufacturing downstream purification studies. Based on the analyses of these studies, this position will be expected to develop and test new hypotheses to improve the fundamental understanding of recovery and purification processes. This position will support process validation, quality by design, regulatory approaches, and quality systems. This position will be expected to prepare internally reviewed technical reports, make oral presentations to scientists and management, and publish externally. The Senior Associate Scientist will be responsible for executing operational efficiency improvements and planning and implementing improvements across Bioprocess R&D work processes. The successful candidate must be able to endorse change to business infrastructure to ensure pipeline, legacy and technology success.

ORGANIZATIONAL RELATIONSHIPS
This position requires highly motivated individuals with the ability to work closely with other members of the laboratory and the department in a matrix team environment. This position will collaborate with pilot plant and manufacturing staff on experimental studies, clinical manufacturing, and process validation, including work with external contract manufacturing organizations.

Must-Have
  • BS (2+ years experience) or MS degree in a biological or engineering discipline
    (Biotechnology, Biochemistry, Chemical/Biochemical Engineering, or equivalent)
  • 0-2 years experience in recombinant protein/biomolecule purification process development, technology transfer and/or bioprocess manufacturing required.
  • Demonstrated ability to drive for results and generate innovative research programs
    independently


Nice-to-Have
  • Applicants should be bright, organized, self-motivated, and capable of working
    independently, and in a collaborative environment.
  • The successful candidate will possess strong oral and written communication skills.
    Diverse work experience recovering recombinant proteins/biomolecules from mammalian and microbial/yeast cultures.
  • Experience transferring Biotherapeutic processes to pilot plants or manufacturing
    organizations, and knowledge of data acquisition and controls systems in these
    environments is desirable.


PHYSICAL/MENTAL REQUIREMENTS

This position will require standing for long periods of time in a laboratory setting. Long periods of sitting at computer work station are required. Occasional lifting of equipment may be required. Occasional travel to vendor worksites may be required.

Work Location Assignment: On Premise

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Relocation assistance may be available based on business needs and/or eligibility.

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Pfizer requires all U.S. new hires to be fully vaccinated for COVID-19 prior to the first date of employment. As required by applicable law, Pfizer will consider requests for Reasonable Accommodations.

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Research and Development
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