Research Associate / Senior Research Associate, Drosophila

Employer
University of Bristol
Location
Bristol, United Kingdom
Salary
Grade - £35,333
Closing date
Dec 1, 2022

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Sector
Science, Life Sciences, Cell and Molecular Biology, Veterinary Medicine, Pharmaceutical, Business Development
Hours
Full Time
Organization Type
University and College
Jobseeker Type
Academic (e.g. 'Lecturer')
The role

A postdoc position is available to join the group of Eugenia Piddini to investigate the cell biology of cell competition in Drosophila .

Research in the Piddini group seeks to understand the mechanisms and function of cell competition and how it modulates cell colonization in tissues and organs. We use an integrated approach that combines genetics and whole tissue in vivo studies in Drosophila with in vitro quantitative approaches using mammalian cells ( http://research-information.bristol.ac.uk/en/person/eugenia.piddini ). Our ultimate goal is to identify how cell competition can be harnessed to develop novel therapeutic strategies in cancer and in regenerative medicine.

What will you be doing?

We are seeking to appoint an outstanding post-doc to investigate the mechanisms and signaling pathways involved in cell competition using Drosophila genetics and in vivo models of cell competition. The project will investigate the cell biology underpinning cell competition. A focus of this work will be on the oxidative stress response and on proteotoxic stress, which our group have discovered are sufficient to induce the loser status and to trigger the elimination of cells activating this response by wild-type cells.

You should apply if

Applicants should be highly motivated and have a substantial track record of productivity and international experience. They should have a PhD in a relevant subject area or be close to completion of their degree.

Prior expertise in cell and/or developmental biology or experience in cell signaling are required. Prior experience with Drosophila models is favoured but is not required.

Applications should include a CV and a brief statement outlining key areas of expertise and reasons why you would like to join our group.

We welcome applications from all members of our community and are particularly encouraging those from diverse groups, such as members of the LGBT+ and BAME communities, to join us.

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