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Principal/Senior Scientist, Upstream Viral Vector

Employer
Life Science People
Location
Portola Valley, CA
Closing date
Nov 26, 2022

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Sector
Science
Organization Type
Corporate
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Life Science People have partnered with a clinical stage biotechnology company who discovers and develops allogeneic gamma delta T cell therapies for cancer. The client is seeking a Principal/Senior Scientist, Upstream Viral Vector who will contribute to the advancement of the production platform by developing, characterizing, and optimizing viral vector production procedures designed to support research and manufacturing pipelines.

This role requires:

* Advanced degree with a background in biology, biomedical engineering, biochemistry, cell & molecular biology, or related life science field is required. Doctoral degree or master's degree with 2+ years or 4+ years post-graduate experience, respectively.
* Considerable direct experience with viral vector production applications is required. Candidates having prior experience with cell line development or media optimization will be given strongest preference.
* Experience in working in a BSL-2 environment is required.
* Candidates having previous experience with suspension cultures and stirred-tank bioreactor systems will be given strongest preference.
* Familiarity with current principles and technical platforms for monitoring cell growth, viability, metabolism, etc., is expected.
* Familiarity with factorial experimental design and DOE software (JMP, Design-Expert, etc.) is desired.
* Experience with retroviral transgene design and optimization would be useful.
* Previous experience conducting technology transfers to external CMOs or adapting client-derived upstream process as a part of a CMO is desirable.
* Flow cytometry, ELISA, and qPCR experience is desirable.

Please note, that we are considering all Principal/Senior Scientist, Upstream Viral Vector on an on-site basis, however they must have the ability to commit to full time employment in the US.

If you are genuinely interested in contributing then please share your resume for immediate consideration!
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