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Research Scientist I - Viral Genomics Group, Sabeti Lab

Broad Institute
Somerville, MA
Closing date
Nov 26, 2022

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Science, Pharmaceutical, Laboratory
Organization Type
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Job Description

The Broad Institute of MIT and Harvard is the world's leading biomedical research institute dedicated to the bold mission of using the full power of genomics to transform the understanding and treatment of disease. The Broad Institute seeks to describe all of the molecular components of life and their connections; discover the molecular basis of major human diseases; develop effective new approaches to diagnostics and therapeutics; and disseminate discoveries, tools, methods, and data openly to the entire scientific community. The Broad Institute includes faculty, professional staff, and students from throughout the MIT and Harvard biomedical research communities and beyond, with collaborations spanning more than a hundred private and public institutions in more than 40 countries worldwide.

The Sabeti Lab at Harvard University and the Broad Institute is developing novel genome sequencing methods to track the spread and evolution of viruses, including SARS-CoV-2, and seeks a Research Scientist to help lead this work.
  • Strong molecular biology background and experience performing library construction and sequencing is required.
  • Experience with sequencing data analysis is required.
  • The ability to communicate effectively, work well in a team setting, and a strong desire to contribute to translational research is required.
  • Pathogen handling and sequencing experience is highly preferred.
  • Experience with liquid handling robotics is preferred.

The applicant will manage a small team of research associates and perform experiments to improve and develop novel pathogen genome sequencing techniques. This position is anticipated to be 40% bench work and 60% project and people management. The position offers an exciting opportunity to participate in a dynamic research environment in a fast-paced field of research with opportunities for international travel. Your work will be central to several major research projects, including collaborations with other labs at the Broad Institute, the Massachusetts Department of Public Health (DPH), and the Centers for Disease Control (CDC). This position will also be directly engaged in the work of the New England Center of the Pathogen Genomics Centers of Excellence network created/funded by the CDC, which is intended to foster and improve innovation and technical capacity in pathogen genomics, molecular epidemiology, and bioinformatics to better prevent, control, and respond to microbial threats of public health importance.

This position will allow for professional advancement, skill development, and co-authorship on high-impact publications.

Key Responsibilities:
  • Work independently and with team members to design, lead, and carry out experiments essential to the individual project and the group's collective success.
  • Investigate, learn, and develop new methods and technologies that might be relevant to the project.
  • Analyze and interpret data and provide recommendations on next steps.
  • Consult the literature, team supervisor, and other scientific staff as needed to troubleshoot experiments.
  • Maintain detailed experimental records, documentation, and written protocols.
  • Oversee testing, implementation and monitoring of sequencing workflows including integration of automation using liquid handling robots.
  • Train and supervise junior team members (research associates, undergraduates, new PhD students).
  • Contribute to grant and manuscript writing as needed.

Required Skills:
  • PhD in genetics, genomics, microbiology or related field with 1+ years of related job experience.
  • Excellent communication, organization, and time management skills.
  • Extensive experimental molecular biology experience and familiarity with next-generation sequencing and standard laboratory techniques (e.g. RNA/DNA extraction, PCR, qPCR, gel electrophoresis, etc).
  • High level of initiative and motivation; ability to work independently and as part of a team in a fast-paced, highly collaborative environment.
  • Detail-oriented and able to think creatively to solve problems.
  • Willingness to work flexible hours and adapt to emerging demands.

The Broad Institute will offer visa sponsorship for this opportunity.

All Broad employees, regardless of work location, must be fully vaccinated for COVID-19 by Tuesday, October 12, 2021. Requests for exemption for medical or sincerely held religious beliefs will be considered.

All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or protected veteran status.

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  • Location: Cambridge, MA
  • Type: Full time
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