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Sr. Research Scientist (In-Vivo/Pharmacology)

Employer
Scientific Search
Location
Landenberg, PA
Closing date
Nov 25, 2022

View more

Sector
Science, Pharmaceutical
Organization Type
Corporate
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Sr. Research Scientist

(In-Vivo/Pharmacology)

Location: Newark, DE

Our client is a biopharmaceutical company focused on the discovery, development, and commercialization of novel medicines to meet serious unmet medical needs in oncology and inflammation and autoimmunity. They are committed to the pursuit of research and development excellence to improve the lives of patients, make a difference in health care, and build sustainable value. The Company strives to discover and develop first-in-class and best-in-class medicines-advancing a diverse portfolio of large and small molecules. The Company strives to discover and develop first-in-class and best-in-class medicines-advancing a diverse portfolio of large and small molecules.

Overview

The Research Scientist, Pharmacology executes scientific experiments for oncology drug discovery programs. The role works in a highly interactive organization and is part of oncology drug discovery project teams with representatives from other departments in the organization. The position is responsible for in vivo, ex vivo, and in vitro pharmacological evaluation of compounds using model systems, and implements experiments to explore/validate novel targets. A successful candidate will be able to contribute to experimental design and to conduct in vivo experiments in appropriate syngeneic, xenograft, PDX and humanized models.

Responsibilities

* Optimize appropriate models/assays that evaluate the effectiveness of designated preclinical compounds and guide chemistry SAR (structure-activity relationship) development.
* Conduct in vivo experiments, including animal handling, dosing, and sample collection.
* Perform ex vivo assessments of drug activity
* Data analysis, excellent notebook keeping, and familiarity with data retrieval and input from a database.
* Assist in communicating scientific data to project team members.

Qualifications

* BS or MS degree (or equivalent) in Biology/Pharmacology with 5+ years drug discovery experience.
* Working knowledge of technologies commonly used to evaluate small molecule inhibitors in vitro or in vivo.
* Extensive experience working with common laboratory animals, including small molecule drug administration.
* Excellent computer and data analysis skills.
* Must be able to perform in a fast-paced environment and deliver high quality data in a timely manner.
* Client offers a competitive salary package that is dependent on qualifications and experience as well as a strong benefit package, plus participation in a companywide bonus plan. For immediate consideration and faster response please forward current resume to: sb@scientificsearch.com. Please include job #17504 in subject line. Please note that all candidates applying must be a US Citizen or Permanent Resident. Client will NOT sponsor.
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