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Associate Scientist, Protein Biochemistry

GILEAD Sciences
San Mateo County, CA
Closing date
Jan 27, 2023

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Science, Chemistry, Biochemistry
Organization Type
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For Current Gilead Employees and Contractors:
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At Gilead we believe every employee deserves a great leader. As a people leader now or in the future, we expect that you will model and create an environment of inclusion, be intentionally focused on the hiring, development, growth and retention of talent, and empower teams to align and achieve goals.Job Description
The Protein Therapeutics Department in Gilead is looking for an Associate Scientist with protein purification and biochemistry expertise. The candidate will join the growing Protein Biochemistry group to deliver high-quality recombinant proteins to enable small-molecule and large-molecule drug discovery campaigns.

The scientist will be a key contributor to project teams focused on new therapies in Immunology, Oncology, and Virology. The primary role will be to express and purify recombinant forms of intracellular and extracellular target proteins and characterize their properties with guidance from senior staff members. The scientist will analyze and interpret the data to trouble shoot and optimize the expression/purification procedures to meet the QC requirements. The candidate will have the opportunity to interact closely and collaborate across all functions of Drug Discovery-Biology, Biologics Discovery, Structural and Computational Biology, and Biophysical and Biochemical Assay.

The position will require the scientist to work creatively, collaboratively, and in a fast-paced environment. He/she will also be encouraged to test and implement new technologies that further enhance the capabilities of the Protein Biochemistry team or address challenges in protein generation.

Education and Technical Skills:
  • MS with 3+ years OR BS with 5+ years of industry experience in a related scientific discipline, such as protein biochemistry and structural biology.
  • Hands-on experience of expressing and purifying quality proteins from bacterial and/or insect cells is required.
  • Training in classical protein purification processes and techniques (affinity, ion exchange, size exclusion chromatography using AKTA chromatographic instruments) as well as knowledge of protein analytical tools (SDS-PAGE analysis, Western blot, HPLC, DLS, DSF, Mass Spectrometry) is required.
  • Excellent communication and interpersonal skills; works independently and as a team player.
  • Attention to detail, accurate record keeping, and good lab citizenship practices are essential.
  • Prior experience with membrane protein purification and characterization is a plus but not required.
  • Prior experience with high-throughput protein expression and purification is a plus but not required.
For jobs in the United States:
As an equal opportunity employer, Gilead Sciences Inc. is committed to a diverse workforce. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, gender, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job related characteristics or other prohibited grounds specified in applicable federal, state and local laws. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans' Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact for assistance.
Following extensive monitoring, research, consideration of business implications and advice from internal and external experts, Gilead has made the decision to require all U.S., Canada, Australia, Singapore, and Hong Kong employees and contractors to receive the COVID-19 vaccines as a condition of employment. "Full vaccination" is defined as two weeks after both doses of a two-dose vaccine or two weeks since a single-dose vaccine has been administered. Anyone unable to be vaccinated, either because of a sincerely held religious belief or a medical condition or disability that prevents them from being vaccinated, can request a reasonable accommodation.

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Our environment respects individual differences and recognizes each employee as an integral member of our company. Our workforce reflects these values and celebrates the individuals who make up our growing team.

Gilead provides a work environment free of harassment and prohibited conduct. We promote and support individual differences and diversity of thoughts and opinion.
For Current Gilead Employees and Contractors:
Please log onto your Internal Career Site to apply for this job.
  • Location: United States - California - Foster City
  • Type: Full time
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