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Head of Chemistry - siRNA

Scientific Search
Somerville, MA
Closing date
Jan 27, 2023

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Science, Chemistry
Organization Type
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Head of Chemistry - siRNA
Location: Boston, MA (Relocation Offered)

Scientific Search has partnered with a Cambridge, MA based Stealth Mode Biotech company that has raised a substantial amount of money and is growing quickly. They are seeking a Head of Chemistry that will have broad range of responsibilities across strategy, talent, and pipeline development.

This Role Offers:
  • Reports directly to a well-known CSO
  • Ability to establish and hire a world class Chemistry Team
  • Excellent Compensation package including industry competitive base, bonus and early stage equity package.
  • Fantastic Medical Benefits, 401k matching, etc.

  • Highly self-motivated, creative, and critical thinking to solve complex technical and scientific problems with excellent attention to detail
  • Ability to build strong, inclusive relationships in highly collaborative, multidisciplinary teams to effectively drive early drug discovery initiatives
  • Project team leadership: setting strategy and driving programs to key decision points
  • Develop and execute synthesis of novel chemical modifications and delivery modalities for siRNA
  • Develop and execute research effort on our extrahepatic delivery platform
  • Synthesis of lipids, small molecules, carbohydrates, and other nucleoside building blocks to be used for RNA delivery and chemical stabilization
  • Work closely with our internal RNAi platform teams and external collaborators including CRO's to execute research on siRNA delivery

  • PhD degree: relevant life sciences discipline
  • 10+ years of relevant experience
  • Familiarity with siRNA, ASOs and gene silencing
  • Exceptional understanding of biology concepts and chemical application to solve biological problems
  • Experience in large molecule drug discovery and in early target discovery and validation

For immediate consideration please email Kevin Wasser, at

Be sure to check out all of our other current openings at
  • Type: Direct Hire
  • Category: Biopharmaceutical Company
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