Principal/Sr Principal Pharmacometrics

Job Description

The Pharmacometrics community at Novartis comprises a group of about 80 quantitative scientists supporting a portfolio of more than 80 clinical development projects in 10 therapeutic areas every day. Quantitative sciences are a critical part of bringing these new medicines to patients. Pharmacometric Scientists bring innovative modeling and simulation skills to every aspect of clinical drug development over a wide range of disease areas and drug modalities. We are dedicated to creating a collaborative and supportive culture where teamwork and learning is emphasized and innovative problem solving is encouraged. Come and join an industry leader where you will have the opportunity to grow and contribute as a quantitative drug development scientist in early- and late-stage projects.

The Principal/Senior Principal Pharmacometrician leads the planning, execution, and delivery of Pharmacometrics strategy on clinical projects within (early/full) clinical development. In this role, you will be responsible for the discussion and implementation of Pharmacometrics methodologies that successfully address the Novartis Institutes for Biomedical Research (NIBR) and Global Drug Development (GDD) objectives on the assigned projects. You will provide Pharmacometrics support for regulatory submissions and supply to drug development decisions with internal and external partners and work with experienced pharmacometricians to collaborate with cross-functional international teams to develop quantitative strategies and will also have the opportunity to explore innovative pharmacometrics methodologies that optimally address the research and development objectives.

What you’ll be doing: Your responsibilities include, but are not limited to:
• Providing exploratory data and modeling analyses for clinical projects
• Contextualizing the modeling question with the relevance to drug and disease biology
• Developing an understanding of drug development applied to scoping relevant questions for Pharmacometrics analysis
• Helping colleagues with review and validation of programs and outputs
• Communication of modeling to project teams in multiple settings such as decision board meetings, small sub-teams, etc.
• Training in good clinical practice for data handling and analysis
• Learning and developing new quantitative analysis methods and application to practical situations in drug development
• Developing posters, publications, presentations for internal and external conferences

This position will be located at the East Hanover, NJ site and will not have the ability to be located remotely. This position will require 0% travel as defined by the business (domestic and/ or international).

Diversity & Inclusion / EEO

The Novartis Group of Companies are Equal Opportunity Employers and take pride in maintaining a diverse environment. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, representative of the patients and communities we serve, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.

Minimum Requirements

What you’ll bring to the role:
• Ph.D. in Pharmacology, Biology, Engineering, Mathematics, Statistics, or a field with significant modeling-related content (or equivalent) with 2+ years modeling related activity in mathematical /statistical modeling with strong working knowledge / experience with R / MATLAB / NONMEM / Monolix.
• Proven ability for innovative problem solving, strong fundamentals in mathematical modeling, collaboration skills across functional areas and good communication skills to both quantitative and non-quantitative scientists.

Why Novartis
766 million lives were touched by Novartis medicines in 2021, and while we’re proud of this, we know there is so much more we could do to help improve and extend people’s lives.

We believe new insights, perspectives and ground-breaking solutions can be found at the intersection of medical science and digital innovation. That a diverse, equitable and inclusive environment inspires new ways of working.

We believe our potential can thrive and grow in an unbossed culture underpinned by integrity, curiosity and flexibility. And we can reinvent what's possible, when we collaborate with courage to aggressively and ambitiously tackle the world’s toughest medical challenges. Because the greatest risk in life, is the risk of never trying!
Imagine what you could do here at Novartis!

Commitment to Diversity & Inclusion:
Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve.

Accessibility and Reasonable Accommodations: The Novartis Group of Companies are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or in order to perform the essential functions of a position, please send an e-mail to [email protected] call +1 (877)395-2339 and let us know the nature of your request and your contact information. Please include the job requisition number in your message.

The pay range for this position at commencement of employment is expected to be between $136,800-205,200 a year; however, base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. The total compensation package for this position may also include other elements, including a sign-on bonus, restricted stock units, and discretionary awards in addition to a full range of medical, financial, and/or other benefits (including 401(k) eligibility and various paid time off benefits, such as vacation, sick time, and parental leave), dependent on the position offered. Details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base salary (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.