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Senior Scientist - Integrated Predictive Science

Groton, Connecticut
Closing date
May 28, 2023

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Science, Pharmaceutical
Full Time
Organization Type
Jobseeker Type
Why Patients Need You

Pfizer's purpose is to deliver breakthroughs that change patients' lives. Research and Development is at the heart of fulfilling Pfizer's purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. In Analytical Research & Development you will apply innovative measurement science, data analytics and process development capabilities to accelerate and bring the best-in-class medicines to patients around the world.

What You Will Achieve

As a Senior Scientist in Analytical Research & Development you will make significant contributions in the development and implementation of advanced predictive sciences to support the development and manufacturing operations for the drug product area. The ideal candidate will have extensive knowledge of mathematical modeling at first principle as well as data driven ones (machine learning, PCA/PLS, etc.) or combination of both (hybrid models). Extensive coding experience with programming languages such as Python/Matlab is a key skill for success in this role. Direct experience with online applications or continuous manufacturing would be an advantage. Experience in the pharmaceutical industry or a regulated environment would also be beneficial.

How You Will Achieve It

  • Evaluate innovative technologies that keep us at the forefront of predictive science.
  • Develop models, logic and control strategies needed to progress small molecule products in the pipeline.
  • Manage development, qualification, validation, and transfer of mathematical models in support of a diverse portfolio in varying stages of clinical development of drug products.
  • Regularly contribute and influence at the project team level.
  • Prepare and review technical documents, including validation protocols and reports, analytical test procedures, investigation reports, and change controls.
  • Work collaboratively and in a wide range of matrix teams both within Pfizer and externally. Analyze and communicate experimental results both orally and in written reports to colleagues and management.
  • Support formulation development, generate analytical data to be used for regulatory submissions, participate in technology transfer activities to manufacturing sites and provide formulation support in developing new products using batch and continuous processing technologies.
  • Review and verify scientific experiments and data documented in electronic laboratory notebooks and technical reports.



  • PhD degree in an engineering or other physical sciences, with specific focus on mathematical modeling.
  • 0-3 years of demonstrated experience with model development and implementation
  • Demonstrated experience coding in Python/Matlab language as well as version control through Git.
  • Creative problem solving and software troubleshooting experience.
  • Strong written and verbal communication skills.
  • Strong collaboration skills and working in a matrix environment.


  • Experience in the pharmaceutical industry and working in a regulated environment.
  • Experience with querying large data sets from relational databases (MySQL, etc.).
  • Experience with containerized microservices development and deployment via Docker and Kubernetes.

Non-standard work schedule, travel or environment requirements
  • Do not anticipate more than 10% travel.
\nRelocation support available\n
Work Location Assignment: On Premise

Relocation assistance may be available based on business needs and/or eligibility.

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Research and Development


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