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Senior Director, Anti-Infectives Research Unit

Pearl River, New York
Closing date
Jun 2, 2023

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Full Time
Organization Type
Jobseeker Type
Why Patients Need You

Pfizer's purpose is to deliver breakthroughs that change patients' lives. Research and Development is at the heart of fulfilling Pfizer's purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best - in - class medicines to patients around the world.

What You Will Achieve

Working with the Portfolio Strategy head and leadership team, the project leader will would be responsible for building and executing innovative scientific project strategies to successfully deliver high quality, differentiated clinical assets through Proof of Concept (POC) in order to address unmet medical needs in infectious disease.

How You Will Achieve It

  • Exhibit substantial scientific and operational bandwidth simultaneously leading up to 3 projects ranging from lead discovery through clinical proof-of-concept.
  • Exhibit significant learning agility and build deep knowledge around molecular targets and disease biology for the programs they lead. The project leader is responsible for championing innovative scientific strategies to deliver differentiated medicines.
  • Responsible for determining the most effective modality (small molecule, biologic, etc) for a given mechanism considering both speed to market and sustainability of differentiation in the market place.
  • Leverage their experience to not only lead internal asset programs, but also programs focused on the development of in-licensed or partnered assets. Additionally, the project leader may be responsible for managing the scientific and logistical aspects of these collaborations or partnerships.
  • Responsible for managing investment risk in individual projects through early identification of key questions and the subsequent use of human genetic data and preclinical pharmacological tools to build confidence in rationale and safety.
  • Build deep competitive intelligence around targets and leverage this knowledge to develop preclinical and clinical differentiation strategies to support the business units' case for investment.
  • Strive to expedite each project from inception to POC to ensure market positioning and maximal profitability over the life of the medicine.
  • Identify major operational and logistical risks and develop effective mitigation options.
  • Inspire strategic and operational excellence from teams supporting early candidate development programs. This will likely include working with partners in different geographic locations.
  • Help coordinate regulatory strategy for projects and may author key regulatory submission documents (IND, IB, position paper, response letters, etc) needed to support candidate development.
  • Coordinate with research and commercial leadership teams to ensure smooth project transitions and alignment on the project objectives and deliverables
  • Build, manage and inspire high performing teams that foster innovation and professional development of others.
  • Communicate effectively. Keep leadership, partners and team members well informed of strategy and progress. Represent projects and assets to governance organizations, external scientific advisors and potential partners.
  • Contribute to the broader RPL community through sharing best-practice and may mentor and coach other project leaders as required



  • PhD or MD preferred
  • 10 or more years of drug discover experience in roles of increasing leadership responsibility
  • Prior knowledge and experience from early discovery through Phase 2 clinical development
  • Experience leading matrix drug discovery teams
  • Strong interpersonal communications and negotiation skills.

Relocation assistance may be available based on business needs and/or eligibility.

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Research and Development


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