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ADC chemist

Southern Research
Irondale, AL
Closing date
Sep 30, 2023

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Science, Chemistry, General Chemistry
Organization Type
ADC Chemist

General Summary

Southern Research is seeking an ADC Chemist with a passion for moving science in drug discovery. As part of our Scientific Platforms Division, the Antibody Discovery Scientist contributes to a team of scientists to identify and characterize antibodies (including nanobodies) and other biologics against therapeutic targets.

Essential Duties & Responsibilities
  • Lead efforts to discover and advance antibodies showing desired function at therapeutic targets
  • Establish and perform protocols for Ab screening and characterization including RNA isolation from PBMCs, Ab library construction, plate-based assays for Ab screening (ELISA, iQue Screener, BLI, etc.), small scale Ab expression and purification.
  • Perform assays to characterize antibody function
  • Work with computational scientists and molecular biologists to optimize and humanize antibodies
  • Establish and perform efficient methods for the above, including applying automated methods
  • Work across departments and functional roles to meet project goals and timelines

Requirements/Minimum Qualifications
  • Education & Experience
    • Bachelors or master's degree in Molecular Biology, Biochemistry, Protein Chemistry or related field and 10+ years' experience OR PhD degree and 3-5 years' experience in antibody discovery and characterization
  • Possess knowledge and experience in early stage antibody drug development
  • Excellent communication skills, written and verbal

Physical Demands

This position requires significant physical abilities including (but not limited to):
  • Standing, walking or climbing for extended periods of time
  • Ability to sit for extended periods of time without being able to leave the work area
  • Lifting, pulling, or pushing objects
  • Perform repetitive activities
  • Fine motor skills and manual dexterity
  • Ability to perform work utilizing a computer for extended periods of time
  • Ability to utilize required PPE in lab environment
  • This position is a laboratory environment and requires the use of personal protective equipment (PPE) including:
    • Safety glasses
    • Laboratory coats
    • Nitrile and latex gloves (varies based on tasks)

Certifications, Licenses & Registrations
  • None required

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