ADC chemist

ADC Chemist

General Summary

Southern Research is seeking an ADC Chemist with a passion for moving science in drug discovery. As part of our Scientific Platforms Division, the Antibody Discovery Scientist contributes to a team of scientists to identify and characterize antibodies (including nanobodies) and other biologics against therapeutic targets.

Essential Duties & Responsibilities

• Lead efforts to discover and advance antibodies showing desired function at therapeutic targets
• Establish and perform protocols for Ab screening and characterization including RNA isolation from PBMCs, Ab library construction, plate-based assays for Ab screening (ELISA, iQue Screener, BLI, etc.), small scale Ab expression and purification.
• Perform assays to characterize antibody function
• Work with computational scientists and molecular biologists to optimize and humanize antibodies
• Establish and perform efficient methods for the above, including applying automated methods
• Work across departments and functional roles to meet project goals and timelines

Requirements/Minimum Qualifications

• Education & Experience
  • Bachelors or master's degree in Molecular Biology, Biochemistry, Protein Chemistry or related field and 10+ years' experience OR PhD degree and 3-5 years' experience in antibody discovery and characterization
• Possess knowledge and experience in early stage antibody drug development
• Excellent communication skills, written and verbal

Physical Demands

This position requires significant physical abilities including (but not limited to):

• Standing, walking or climbing for extended periods of time
• Ability to sit for extended periods of time without being able to leave the work area
• Lifting, pulling, or pushing objects
• Perform repetitive activities
• Fine motor skills and manual dexterity

• Ability to perform work utilizing a computer for extended periods of time
• Ability to utilize required PPE in lab environment
• This position is a laboratory environment and requires the use of personal protective equipment (PPE) including:
  • Safety glasses
  • Laboratory coats
  • Nitrile and latex gloves (varies based on tasks)

Certifications, Licenses & Registrations

• None required