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Post-Doctoral Research Fellow - Hatch Lab

Employer
Fred Hutchinson Cancer Research Center
Location
Wallingford, WA
Closing date
Feb 13, 2024

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Sector
Pharmaceutical, Laboratory
Organization Type
Corporate
Overview

Fred Hutchinson Cancer Center is an independent, nonprofit organization providing adult cancer treatment and groundbreaking research focused on cancer and infectious diseases. Based in Seattle, Fred Hutch is the only National Cancer Institute-designated cancer center in Washington.

With a track record of global leadership in bone marrow transplantation, HIV/AIDS prevention, immunotherapy and COVID-19 vaccines, Fred Hutch has earned a reputation as one of the world's leading cancer, infectious disease and biomedical research centers. Fred Hutch operates eight clinical care sites that provide medical oncology, infusion, radiation, proton therapy and related services, and network affiliations with hospitals in five states. Together, our fully integrated research and clinical care teams seek to discover new cures to the world's deadliest diseases and make life beyond cancer a reality.

At Fred Hutch we value collaboration, compassion, determination, excellence, innovation, integrity and respect. These values are grounded in and expressed through the principles of diversity, equity and inclusion. Our mission is directly tied to the humanity, dignity and inherent value of each employee, patient, community member and supporter. Our commitment to learning across our differences and similarities make us stronger. We seek employees who bring different and innovative ways of seeing the world and solving problems. Fred Hutch is in pursuit of becoming an anti-racist organization. We are committed to ensuring that all candidates hired share our commitment to diversity, anti-racism and inclusion.

Fred Hutch and the Hatch lab are committed to cultivating a workplace in which diverse perspectives and experiences are welcomed and respected. We encourage individuals with diverse backgrounds to apply. Fred Hutch has more than 200 postdoctoral fellows working in labs across five research divisions. We provide postdocs the opportunity to work on the cutting edge of biomedical research in a supportive, collaborative environment with faculty and staff who are dedicated to helping trainees achieve their career goals. In addition, the Student/Postdoc Advisory Committee and the Office of Scientific Career Development offer diverse mentoring and career development opportunities.

A post-doctoral research fellow position is available in the Hatch Lab in the Basic Sciences Division. We study the structure and dynamics of the human nuclear envelope, with a primary interest in why and how nuclear membranes rupture and repair, and how defects in nuclear membrane stability impact cancer development (Gunn, Yashchenko, and Hatch, bioRxiv, 2023, DiPeso et al., bioRxiv, 2023, Mammel, Gunn, and Hatch, LSA, 2021; Maciejowski and Hatch, Ann Rev Cell Dev Biol, 2020). The Hatch lab uses a variety of techniques to achieve these goals with a focus on microscopy, automated image analysis, and cell-based tool development.

Responsibilities

The fellow will be responsible for defining, in discussion with Dr. Hatch, and executing a project related to the core interests of the lab with the goal of developing a new line of inquiry that the fellow could start their own research program with, if desired. Current areas of interest are: identifying and characterizing the molecular mechanism of proteins that regulate nuclear membrane rupture and repair, determining how chromatin regulates nuclear lamina organization and membrane stability in micronuclei, identifying and defining the mechanisms of the cellular consequences of micronucleation and nucleus rupture, and developing new models to investigate how nuclear rupture and micronucleation impact cell transformation and tumor progression. The development of collaborative projects with other labs at Fred Hutch is of substantial interest. The fellow will also be required to apply to relevant fellowship opportunities within Fred Hutch and from outside organizations.

Strong candidates will have demonstrated excellent abilities to independently design, execute, and interpret experiments, synthesize literature into working models, identify and communicate with scientists outside their lab to learn new techniques or topics, and effectively communicate the significance of their research in oral and written presentations.

Qualifications

* A PhD in biology is required.
* First authorship on a published manuscript, or one in submission, is required.
* The ability to clearly and efficiently communicate data, both in writing and verbally, is required.
* The ability to work independently is required.
* Experience with microscopy and quantitative image analysis is strongly preferred.
* Experience with immunological labeling techniques, including western blotting, flow cytometry, and immunofluorescence, is preferred.

A statement describing your commitment and contributions toward greater diversity, equity, inclusion, and antiracism in your career or that will be made through your work at Fred Hutch is requested of all finalists.

The annual base salary range for this position is from $67,728 to $100,000 and pay offered will be based on experience and qualifications.

This position may be eligible for relocation assistance.

Fred Hutchinson Cancer Center offers employees a comprehensive benefits package designed to enhance health, well-being, and financial security. Benefits include medical/vision, dental, flexible spending accounts, life, disability, retirement, family life support, employee assistance program, onsite health clinic, income-based child care subsidy, tuition reimbursement, paid vacation (22 days per year), paid sick leave (up to 30 calendar days per occurrence of a qualifying reason), paid holidays (13 days per year), and paid parental leave (up to 4 weeks).

Our Commitment to Diversity

We are proud to be an Equal Employment Opportunity (EEO) and Vietnam Era Veterans Readjustment Assistance Act (VEVRAA) Employer. We are committed to cultivating a workplace in which diverse perspectives and experiences are welcomed and respected. We do not discriminate on the basis of race, color, religion, creed, ancestry, national origin, sex, age, disability (physical or mental), marital or veteran status, genetic information, sexual orientation, gender identity, political ideology, or membership in any other legally protected class. We are an Affirmative Action employer. We encourage individuals with diverse backgrounds to apply and desire priority referrals of protected veterans. If due to a disability you need assistance/and or a reasonable accommodation during the application or recruiting process, please send a request to Human Resources at hrops@fredhutch.org or by calling 206-667-4700.

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