Skip to main content

Postdoctoral Scholar- Jain Lab

Employer
Gladstone Institutes
Location
San Bruno, CA
Closing date
May 30, 2024

View more

Sector
Pharmaceutical, Laboratory
Organization Type
Corporate
Category:Postdoc
Lab/Area:Jain Lab

Description:

The Jain Lab (https://ishajainlab.com) is looking for motivated, hard-working and curious applicants. At a high level, we study how organisms interact with their environments - how "what we breathe" and "what we eat" affects our metabolism and disease progression. More specifically, we are focused on oxygen and vitamin/cofactor metabolism. We recently discovered that chronic hypoxia (equivalent to living in the mountains of Peru or Nepal) can serve as a therapy for mitochondrial disease. This approach is currently in clinical trials. This work has inspired a broader set of research directions ranging from fundamental biochemistry to animal physiology.

The questions we ask:

1. How do cells and organisms sense oxygen or vitamin levels? Are there novel oxygen sensors and vitamin sensors to be found?

2.How does the body adapt to variations in oxygen levels? Or vitamin levels?

3.When the supply and demand of oxygen or vitamins becomes mismatched, how does this contribute to disease?

4.Can we "turn the oxygen and vitamin dials" as creative new therapies?

5. What is the most practical form of turning these concepts into translatable therapies?

The approach we take: CRISPR screens, metabolomics, classical biochemistry/molecular biology, animal physiology and beyond.

Post-docs will be encouraged to lead independent projects resulting in high impact publications, present at conferences and prepare for long-term careers in academia or industry.

Hiring Range:

Salary range (DOE):

$66,560-$79,490

https://gladstone.org/training/postdocs

Postdocs are currently receiving an additional $10K housing allowance.

If you are interested in working on exciting problems related to oxygen/vitamins/aging, email Dr. Jain atIsha.Jain@gladstone.ucsf.eduwith a short description of your past research experiences and a resume/CV.

Gladstone Perks & Benefits
  • People -work with talented, committed, and supportive teammates within an organization that values each member of its community.
  • A meaningful place to grow and learn -whether it's your professional skills or scientific knowledge, we have the resources and environment to advance either so you can better support Gladstone's mission to drive a new era of discovery in disease-oriented science and to mentor tomorrow's leaders in an inspiring and diverse environment.
  • Healthy work/life balance -you are highly engaged and productive at work because you can have time to recharge and enjoy a vibrant life outside of work.
  • Compensation -competitive salary. Title and salary will be commensurate with education and experience.
  • Excellent benefits -generous medical, dental, vision, retirement plan, paid vacation, commuter benefits, access to free shuttle transportation.

Gladstone is committed to providing equal employment opportunities to all employees and applicants for employment without regard to race, color, sex, religion, national origin, ancestry, age, marital status, medical condition, physical or mental disability, veteran status, sexual orientation, or any other non-job related characteristic. We make all employment decisions so as to further this principle of equal employment.

Get job alerts

Create a job alert and receive personalized job recommendations straight to your inbox.

Create alert