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Assistant Research Professor in Anatomy, Cell Biology & Physiology

Employer
Indiana University
Location
Woodbridge, IN
Closing date
Apr 16, 2024
Title Assistant Research Professor in Anatomy, Cell Biology & Physiology Specific Title Appointment Type Scientist Track Faculty Department IUSM - Anatomy, Cell Biology & Physiology Campus IU School of Medicine Indianapolis Position Summary

The Lasagna-Reeves lab, a member of the Stark Neuroscience Research Institute (SNRI) at Indiana University School of Medicine, invites applications for a faculty position at the rank of Research Assistant Professor to develop a project to identify mechanisms involved in Resiliency against Alzheimer's disease.

Pathological aggregation of the microtubule-associated protein tau and the preponderance of neurofibrillary tangles (NFT) or other inclusions containing tau are the defining histopathological features of Alzheimer's disease and more than 20 other neurodegenerative tauopathies. Therefore, the study of the physiological and pathological function of tau is key to understanding and treating these neurodegenerative diseases. Hence, the main focus of the Lasagna-Reeves Lab is to comprehensively elucidate the role that tau physiology plays in neurodegenerative tauopathies.

The Lasagna-Reeves Lab works on a study characterizing the mechanisms involved in tau aggregation and protection against AD. To pursue this, the lab combined in vitro structural and cellular techniques with mouse genetic manipulations and human neuropathology to determine the pathways involved in resiliency against AD.

The lab is looking for investigators with expertise in molecular biology, biochemistry, mouse and behavior, spatial transcriptomic, and histological analysis in the context of neurodegenerative diseases. The successful candidate will join an already established team that includes senior and junior scientists, as well as postdocs and Ph.D. students who will also be involved in this project.

Primary Duties and Responsibilities

* Responsible for developing an end-to-end project dissecting the mechanisms involved in resiliency against AD.
* Lead, develop, and troubleshoot specific analyses.
* Multi-task projects and keep pace in a dynamic research environment.
* Present research advances at a variety of internal and external seminars.
* Lead manuscript writing.
* Direct, coordinate, and supervise laboratory personnel.
* Mentor students and research staff

As the nation's largest medical school, IUSM is committed to being an institution that not only reflects the diversity of the learners we teach and the patient populations we serve but also pursues the values of diversity, equity, and inclusion that inform academic excellence. We desire candidates who enhance our representational diversity, as well as those whose work contributes to equitable and inclusive learning and working environments for our students, staff, and faculty. IUSM strives to take an anti-racist stance, regularly evaluating and updating its policies, procedures, and practices to confer equitable opportunities for contribution and advancement for all members of our community. We invite individuals who will join us in our mission to advance racial equity to transform health and well-being for all throughout the state of Indiana.

Indianapolis is the capital and most populous city in the State of Indiana. It is growing economically thanks to a strong corporate base anchored by the life sciences. Indiana is home to one of the largest concentrations of health sciences companies in the nation. Indianapolis has a sophisticated blend of charm and culture with a wonderful balance of business and leisure. The growing residential base is supported by rich amenities and quality of life - the city possesses a variety of professional sports, arts venues, and outdoor recreation areas. Residents of this dynamic city, and surrounding suburbs, enjoy leading educational systems and top-ranked universities, paired with a diverse population. Indianapolis International Airport is a top-ranked international airport, being named "Best Airport in North America" by Airports Council International for many years.

Information about the Department of Anatomy, Cell Biology & Physiology is available at:

https://medicine.iu.edu/anatomy-cell-biology-physiology

Information about the Indiana University School of Medicine is available at:

https://medicine.iu.edu

Basic Qualifications

Doctorate or Terminal degree is required. Must have a Ph.D. or M.D. degree with 3 or more years of postdoctoral experience.

Department Contact for Questions

Inquiries about this position should be sent to Dr. Lasagna Reeves (clasagna@iu.edu)

Additional Qualifications Special Instructions

Please provide a CV and contact information for 3 references.

Priority Application Review Deadline Expected Start Date OAA # IUSM-01952-2024

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