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Senior Scientist - Flow NMR

La Jolla, California
Closing date
Aug 1, 2024

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Full Time
Organization Type
Jobseeker Type

Pfizer's purpose is to deliver breakthroughs that change patients' lives. Research and Development is at the heart of fulfilling Pfizer's purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best in class medicines to patients around the world.


NMR Spectroscopist/Structure Elucidation Scientist

An opening is available for a Reaction Monitoring Flow NMR Scientist in the Structure Elucidation Group, Pharmaceutical Sciences Small Molecule Division of Pfizer Worldwide Research and Development in Groton, CT.

The Pharmaceutical Sciences Small Molecule Structure Elucidation Group supports all areas of drug development. It is responsible for the characterization of drug candidates, formulations, excipients, degradation products and impurities as well as reaction monitoring, developing kinetic models and in situ quantification via NMR. The group interacts with technology and project groups throughout the entirety of Pfizer. In addition to extensive research NMR capabilities, our group also supports a small open access NMR facility. The position will be heavily focused on reaction monitoring, reaction kinetics, structure elucidation and characterization of small organic molecules.

  • Reaction monitoring, developing kinetics models, quantification, elucidate structures and solve scientific questions for small molecules of pharmaceutical interest using multidimensional liquids NMR.
  • Work within a team of disparate scientific disciplines as a functional member (e.g., working closely with mass spectrometrists, NMR spectroscopists, purification scientists, organic chemists, etc.) as a subject matter expert.
  • The individual will be expected to provide strong technical and strategic input and to ensure efficient and timely execution of deliverables.
  • Act as NMR liaison/subject matter expert at portfolio project team meetings.
  • Investigate and implement novel NMR experiments and technologies.
  • Write technical documents.
  • Communicate routinely with chemists within Small Molecule Pharmaceutical Sciences as well as other divisions throughout Pfizer globally.
  • Provide open access NMR support for over 100 chemists and engineers.

  • The successful candidate will have a B.S./M.S. degree with 8-10 years of NMR experience or a Ph.D. degree in chemistry (preferably Organic focused) or equivalent with expertise in small molecule NMR with 1-2+ years of experience.

  • A strong understanding of the theory and application of organic chemistry
  • A strong understanding of the theory and application of NMR spectroscopy.
  • Experience in structural elucidation of small molecules using solution NMR
  • Knowledge of Bruker and Varian NMR systems.
  • Pharmaceutical industry experience desirable.
  • Proven track record of technology implementation as demonstrated by publication/presentation records.
  • Strong communication skills and a demonstrated ability to carry out independent research are required.
  • S trong interest and motivation to learn new technologies and concepts is expected.
  • Experience with NMR processing software (Topspin, Mnova, ACD).
  • Experience with chromatography, mass spectrometry, and molecular modeling is beneficial .

Relocation support available
Work Location Assignment:On Premise

The annual base salary for this position ranges from $88,300.00 to $147,100.00. In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 12.5% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.S. Benefits | ( Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.

Relocation assistance may be available based on business needs and/or eligibility.

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.

Research and Development

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