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Research Associate I - Neurosurgery & Behavior

Employer
The Allen Institute for Brain Science
Location
Times Square, WA
Closing date
Jul 14, 2024

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The mission of the Allen Institute is to unlock the complexities of bioscience and advance our knowledge to improve human health. Using an open science, multi-scale, team-oriented approach, the Allen Institute focuses on accelerating foundational research, developing standards and models, and cultivating new ideas to make a broad, transformational impact on science.

The mission of the Allen Institute for Neural Dynamics is focused on fundamental discoveries in systems neuroscience. We are interested in how the brain builds our understanding of the complex world to guide the flexible behaviors that address our biological needs. The answers will be in terms of defined neuron types and circuits interacting across the whole brain and body. We will develop next-generation methods and theories and employ a team-based approach to discovery neuroscience. Knowledge, data, models, and tools will be widely shared to support the development of therapies for brain disorders.

This Research Associate will be part of the Neurosurgery & Behavior team within the Research Operations department in the Allen Institute for Neural Dynamics. Primary responsibilities include performing aseptic stereotaxic surgical procedures, as well as conducting a variety of behavior training regimens on mice. Good judgment and problem-solving skills are required for recognizing process deviations, participating in troubleshooting and procedure optimization, and operation of complex laboratory instrumentation. The ideal candidate will possess excellent manual dexterity, close attention to detail and a desire to work in a deadline-driven, team-science atmosphere.

The Allen Institute believes that team science significantly benefits from the participation of diverse voices, experiences and backgrounds. High-quality science can only be produced when it includes different perspectives. We are committed to increasing diversity across every team and encourage people from all backgrounds to apply for this role.

Essential Functions
  • Perform various aseptic surgical procedures in mice
  • Perform various behavioral training regimens with mice
  • Involvement in various transgenic technologies employed in the animal facility
  • Pre- and post-operative care for mice
  • Administration of compounds to mice (i.p., s.c., i.m.)
  • Maintenance of health and behavior performance records
  • Follow Standard Operating Procedures (SOPs) and maintain good laboratory practices
  • Maintain accurate laboratory documentation and reporting using established methods
  • Ability to meet aggressive timelines and deliverables in a collaborative environment

Note: Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions. This description reflects management's assignment of essential functions; it does not proscribe or restrict the tasks that may be assigned.

Required Education and Experience
  • Bachelor's degree in neuroscience, biology, or a related field
  • Proven ability to learn and perform, challenging surgical procedures on mice

Preferred Education and Experience
  • 0-2 years of relevant laboratory experience
  • Basic knowledge of mouse genetics and anatomy
  • Manual dexterity and attention to detail
  • Proficiency with Microsoft Office, Microsoft Access
  • Ability to learn custom software systems (LIMS, LabTracks)

Work Environment
  • Exposure to, and handling of, laboratory animals
  • Possible exposure to chemical, biological or other hazardous substances
  • May be required to be available outside of standard working hours (weekends and/or holidays)
  • Possible exposure to BioSafety Level 2 organisms, such as recombinant viruses

Animal Care Services
  • Exposure to and handling of laboratory animals required
  • Pre and post-operative care for mice
  • Administration of compounds to mice (iv, ip, sc, po, im, ro, icv)
  • Perform health assessments of mice
  • Perform euthanasia and tissue collections
  • Perform daily facility maintenance and/or closing procedures

Physical Demands
  • Occasional lifting up to 30 pounds
  • Fine motor movements in fingers/hands to operate computers and other office equipment; repetitive motion with lab equipment
  • Push/pull up to 20 pounds
  • Stooping, bending, crouching
  • Reaching, or climbing ladders

Position Type/Expected Hours of Work
  • This is an essential job and expected to report for work regardless of weather and/or other conditions
  • Occasional evening and weekend hours required
  • This role is currently working onsite and is expected to work onsite for the majority of working hours. The primary work location for this role is 615 Westlake Ave N., with flexibility to work remotely on a limited basis.

Additional Eligibility Qualifications
  • All employees who work with live animals must complete an Occupational Health medical history form and/or consultation with an Occupational Health Provider and receive clearance to work with animals. Depending on your health history and job responsibilities, an annual respiratory health screening and clearance to use a respirator may also be required.

Additional Comments
  • **Please note, this opportunity offers relocation assistance**

Annualized Salary Range
  • $48,100 - $64,150*

* Final salary depends on the required education for the role, experience, level of skills relevant to the role, and work location, where applicable.

Benefits
  • Employees (and their families) are eligible to enroll in benefits per eligibility rules outlined in the Allen Institute's Benefits Guide. These benefits include medical, dental, vision, and basic life insurance. Employees are also eligible to enroll in the Allen Institute's 401k plan. Paid time off is also available as outlined in the Allen Institutes Benefits Guide.

It is the policy of the Allen Institute to provide equal employment opportunity (EEO) to all persons regardless of age, color, national origin, citizenship status, physical or mental disability, race, religion, creed, gender, sex, sexual orientation, gender identity and/or expression, genetic information, marital status, status with regard to public assistance, veteran status, or any other characteristic protected by federal, state or local law. In addition, the Allen Institute will provide reasonable accommodations for qualified individuals with disabilities.

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