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Sr. Research Associate I, Pivotal Purification Process Development

Employer
Gilead Sciences, Inc.
Location
Oceanside, CA
Closing date
Oct 8, 2024
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Sr. Research Associate I, Pivotal Purification Process Development
United States - California - Oceanside

Gilead Sciences, Inc. is a research-based bio-pharmaceutical company that discovers, develops and commercializes innovative medicines in areas of unmet medical need. With each new discovery and investigational drug candidate, we seek to improve the care of patients living with life-threatening diseases around the world. Gilead's therapeutic areas of focus include HIV/AIDS, liver diseases, cancer and inflammation, and serious respiratory and cardiovascular conditions.

Making an impact on a global scale
Inclusion is one of the company's five core values. That's because we know that we are stronger and more innovative at Gilead when we are informed by a diverse set of backgrounds, experiences and points of view. Gilead Sciences is a biopharmaceutical company that discovers, develops and commercializes innovative therapeutics in areas of unmet medical need. The company's mission is to advance the care of patients suffering from life-threatening diseases worldwide.

When you join Gilead, you join our mission to change the world by enabling people to live healthier and more fulfilling lives. Come join a mission-driven bio-pharmaceutical organization that values inclusion and diversity, has a strong portfolio of products, and is constantly #CreatingPossible

For Current Gilead Employees and Contractors:

Please log onto your Internal Career Site to apply for this job.

At Gilead, we're creating a healthier world for all people. For more than 35 years, we've tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer - working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world's biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference.

Every member of Gilead's team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we're looking for the next wave of passionate and ambitious people ready to make a direct impact.

We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together.

Job Description

*At a future date this position will relocate to the corporate HQ in Foster City, CA

Gilead Sciences is seeking a Sr Research Associate I with experience in protein purification process development to support operations at our biologics development.

Essential Duties and Job Functions:
  • Plan and execute assigned experiments that support Process Development activities and project goals.
  • Select appropriate methods and techniques for performing experiments.
  • Develop skills in data analysis and interpreting experiment outcomes including the ability to evaluate data quality and recognize anomalous results.
  • Recommend alternatives, research new methods and techniques and proactively seek out senior personnel to discuss potential solutions to problems.
  • Participate in group meetings and present results, data interpretation and conclusions.
  • Demonstrate strong verbal communication and interpersonal skills including the ability to explain processes used to achieve results of assigned tasks.
  • Work with team oriented, collaborative and problem-solving mindset.
  • Always work with safety in mind.


Knowledge, Experience and Skills:
  • Preferred degree in Chemical/Biochemical Engineering, Biochemistry, Chemistry or a related scientific discipline.
  • Prior experience in biologics purification, with an emphasis on affinity, IEX, and HIC.
  • Prior experience in analytical operations: SEC/HPLC, CE (R/NR), HCP testing is beneficial, but not required.
  • Knowledge of cGMPs, technology transfer, and scaling up bioprocesses.
  • Must be able to work effectively in cross-functional teams.
  • Must demonstrate excellent technical writing skills.
  • Working understanding of downstream process development including centrifugation, normal and tangential flow filtration, chromatography operations, and virus clearance. The ability to demonstrate hands on experience in several of these areas is expected. Experience with multiple modalities (mAbs, bispecifics, fusion and antibody drug conjugates, virus particles) produced in microbial and mammalian expression systems is a plus.
  • Ability to work effectively within the purification team to help design and execute experiments supporting process definition, optimization, and characterization with an increasing level of independence.
  • Ability to collaborate with Technical Operations during technology transfer from process development to GMP manufacturing, including serving as a process development representative during purification operations, providing technical troubleshooting and identifying opportunities for future process and equipment improvements. The candidate will also contribute to the preparation of regulatory filings and process validation and characterization reports.
  • Ability to effectively communicate ideas, project goals and results and should have the ability to proactively identify issues and suggest solutions in a collaborative, multidisciplinary environment. This is a highly collaborative environment where willingness and ability to communicate and work effectively with individuals across various teams is essential.
  • Self-motivated, organized, and enjoy scientific investigation and thinking. The candidate will monitor and contribute to external literature and scientific conferences.


Basic Qualifications:
  • BS degree in a relevant scientific discipline and 2+ years of relevant experience; OR
  • MS degree in a relevant scientific discipline and 0+ years of relevant experience
  • Gilead is an equal opportunity employer.


The salary range for this position is: $84,405.00 - $109,230.00. Gilead considers a variety of factors when determining base compensation, including experience, qualifications, and geographic location. These considerations mean actual compensation will vary. This position may also be eligible for a discretionary annual bonus, discretionary stock-based long-term incentives (eligibility may vary based on role), paid time off, and a benefits package. Benefits include company-sponsored medical, dental, vision, and life insurance plans*.

For additional benefits information, visit:

https://www.gilead.com/careers/compensation-benefits-and-wellbeing

* Eligible employees may participate in benefit plans, subject to the terms and conditions of the applicable plans.

For jobs in the United States:


As an equal opportunity employer, Gilead Sciences Inc. is committed to a diverse workforce. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, gender, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job related characteristics or other prohibited grounds specified in applicable federal, state and local laws. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans' Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact ApplicantAccommodations@gilead.com for assistance.

For more information about equal employment opportunity protections, please view the 'Know Your Rights' poster.

NOTICE: EMPLOYEE POLYGRAPH PROTECTION ACT
YOUR RIGHTS UNDER THE FAMILY AND MEDICAL LEAVE ACT

PAY TRANSPARENCY NONDISCRIMINATION PROVISION

Our environment respects individual differences and recognizes each employee as an integral member of our company. Our workforce reflects these values and celebrates the individuals who make up our growing team.

Gilead provides a work environment free of harassment and prohibited conduct. We promote and support individual differences and diversity of thoughts and opinion.

For Current Gilead Employees and Contractors:


Please log onto your Internal Career Site to apply for this job.

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