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Senior Research Associate I - Protein Therapeutics

Employer
Gilead Sciences, Inc.
Location
Foster City, CA
Closing date
Oct 10, 2024
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Senior Research Associate I - Protein Therapeutics
United States - California - Foster City

Gilead Sciences, Inc. is a research-based bio-pharmaceutical company that discovers, develops and commercializes innovative medicines in areas of unmet medical need. With each new discovery and investigational drug candidate, we seek to improve the care of patients living with life-threatening diseases around the world. Gilead's therapeutic areas of focus include HIV/AIDS, liver diseases, cancer and inflammation, and serious respiratory and cardiovascular conditions.

Making an impact on a global scale
Inclusion is one of the company's five core values. That's because we know that we are stronger and more innovative at Gilead when we are informed by a diverse set of backgrounds, experiences and points of view. Gilead Sciences is a biopharmaceutical company that discovers, develops and commercializes innovative therapeutics in areas of unmet medical need. The company's mission is to advance the care of patients suffering from life-threatening diseases worldwide.

When you join Gilead, you join our mission to change the world by enabling people to live healthier and more fulfilling lives. Come join a mission-driven bio-pharmaceutical organization that values inclusion and diversity, has a strong portfolio of products, and is constantly #CreatingPossible

For Current Gilead Employees and Contractors:

Please log onto your Internal Career Site to apply for this job.

At Gilead, we're creating a healthier world for all people. For more than 35 years, we've tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer - working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world's biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference.

Every member of Gilead's team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we're looking for the next wave of passionate and ambitious people ready to make a direct impact.

We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together.

Job Description

Gilead Sciences Protein Therapeutics Department currently has an exciting opportunity for a highly motivated research associate to join the Protein Science group. The successful candidate is expected to work independently and display professional judgment in all aspects of daily research and presentations. This person will work in collaboration with research project teams to generate and validate potential therapeutic proteins and surrogate tool molecules including bispecific antibodies, immunocytokines and other novel and complex biologics. The candidate should be team-oriented, professional, hard-working, and interested in learning new skills.

Specific Responsibilities and Skills for this Position:

Responsibilities:
  • Perform protein purification, QC, and registration to Genedata Biologics (GDB) to support the preclinical development of biopharmaceutical programs across multiple therapeutic areas.
  • Proactively troubleshoot purification challenges and seek out senior personnel to discuss potential solutions when needed.
  • Prepare technical reports, quantitative analyses, and summaries for entry into Excel, PPT, and ELN formats.
  • Use good oral and written communication skills to relay scientific data and update collaborators of purification status and challenges.
  • Actively participate in group meetings, present the results of one's work, interpret data, and draw conclusions regarding presented material.
  • Maintain awareness of cutting-edge technical developments and scientific knowledge and apply these where possible to improve process efficiency.


Required skills:
  • Strong background in protein sciences and protein biochemistry
  • At least 2 years of direct experience in purifying and characterizing a variety of recombinant proteins, particularly monoclonal antibodies and next generation biologics (e.g., bispecific antibodies, immunocytokines)
  • Hands-on experience in purification techniques including affinity, ion exchange, size exclusion, hydrophobic interaction chromatography using Akta Avant/Pure or BioRad NGC
  • Proficiency with various analytical protein characterization techniques such as SEC-HPLC or UHPLC, SDS-PAGE, Endosafe
  • Ability to perform method development and write protocols
  • Detailed record-keeping is a must
  • Ability to multi-task and work in a fast-paced team environment


Nice to have skills:
  • Experience with other protein characterization technologies (DLS, SEC-MALS, LC/MS, IEX/HIC-HPLC) would be a strong plus
  • Experience in protein formulation utilizing BigTuna or TFF would be a strong plus
  • Experience using autosamplers like CETAC or ALIAS is desired
  • Experience using automated liquid handling systems would be plus


Education and Experience:
MS in Biochemistry, Bioengineering, or related field or BS/BA with 2+ years of relevant experience

The salary range for this position is: $92,820.00 - $120,120.00. Gilead considers a variety of factors when determining base compensation, including experience, qualifications, and geographic location. These considerations mean actual compensation will vary. This position may also be eligible for a discretionary annual bonus, discretionary stock-based long-term incentives (eligibility may vary based on role), paid time off, and a benefits package. Benefits include company-sponsored medical, dental, vision, and life insurance plans*.

For additional benefits information, visit:

https://www.gilead.com/careers/compensation-benefits-and-wellbeing

* Eligible employees may participate in benefit plans, subject to the terms and conditions of the applicable plans.

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As an equal opportunity employer, Gilead Sciences Inc. is committed to a diverse workforce. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, gender, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job related characteristics or other prohibited grounds specified in applicable federal, state and local laws. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans' Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact ApplicantAccommodations@gilead.com for assistance.

For more information about equal employment opportunity protections, please view the 'Know Your Rights' poster.

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PAY TRANSPARENCY NONDISCRIMINATION PROVISION

Our environment respects individual differences and recognizes each employee as an integral member of our company. Our workforce reflects these values and celebrates the individuals who make up our growing team.

Gilead provides a work environment free of harassment and prohibited conduct. We promote and support individual differences and diversity of thoughts and opinion.

For Current Gilead Employees and Contractors:


Please log onto your Internal Career Site to apply for this job.

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