Skip to main content

This job has expired

Principal Scientist - Enzymology

Employer
Abbott Laboratories
Location
San Diego, CA
Closing date
Oct 4, 2024
View more categoriesView less categories
Sector
Science
Organization Type
Corporate
Abbott is a global healthcare leader that helps people live more fully at all stages of life. Our portfolio of life-changing technologies spans the spectrum of healthcare, with leading businesses and products in diagnostics, medical devices, nutritionals and branded generic medicines. Our 114,000 colleagues serve people in more than 160 countries.

Working at Abbott

At Abbott, you can do work that matters, grow, and learn, care for yourself and family, be your true self and live a full life. You'll also have access to:

Career development with an international company where you can grow the career you dream of!

Free medical coverage for employees* via the Health Investment Plan (HIP) PPO

An excellent retirement savings plan with high employer contribution

Tuition reimbursement, the student debt program and education benefit - an affordable and convenient path to getting a bachelor's degree.

A company recognized as a great place to work in dozens of countries around the world and named one of the most admired companies in the world by Fortune.

A company that is recognized as one of the best big companies to work for as well as a best place to work for diversity, working mothers, female executives, and scientists.

The Opportunity

This position works out of our San Diego, CA location in the Infectious Diseases Division.

We are seeking an experienced Principal Scientist to oversee and conduct cutting-edge research in enzymology, to identify, characterize, optimize and develop proteins used for nucleic acid amplification and sample preparation technologies. Your expertise will be crucial in advancing our understanding of enzymatic processes and developing innovative solutions. You'll collaborate with cross-functional teams, establish protocols, and drive scientific excellence.

Responsibilities

Lead protein characterization, optimization and development efforts, from design of experiments through laboratory studies

Perform kinetic, thermodynamic and structure-function studies

Apply computational modeling to drive protein characterization and optimization efforts

Initiate and oversee proteomics efforts in-house and via collaboration

Provide cloning, protein expression, separation and purification expertise

Implement mutagenesis studies to help characterize and optimize proteins of interest

Drive the introduction of new, optimized and/or modified proteins to improve product performance

Design and implement procedures, processes and key performance indicators to monitor, characterize and QC proteins

Provide high level analysis of experimental results

Provide written reports and oral presentations to executives

Ability to work as part of a team with excellent communication skills

Excellent communication and collaboration skills

Required Qualifications

Bachelor's Degree. in Biochemistry/Biophysics/Protein chemistry, or a closely related field and 10 years of experience in similar area.

Preferred Qualifications

Ph.D.in Biochemistry/Biophysics/Protein chemistry, or a closely related field and 10 years of experience.

Minimum ten years of full-time laboratory experience in an industrial setting

Hands-on expertise using kinetic, thermodynamic and structure-function experimental approaches

Expertise with computational modeling of proteins and protein/nucleic acid interactions to drive characterization of protein functionality and to drive the incorporations of protein modifications to improve/alter function

Extensive experience characterizing DNA/RNA interacting/binding proteins

Expertise in optimizing protein expression and purification methods

Expertise in developing, optimizing and performing in vitro enzymatic assays

Experience with high-throughput genetic/molecular screening a plus

Inventive, with ability to implement ideas in the laboratory

Strong problem-solving skills and the ability to analyze complex enzymatic processes

Extensive hands-on experience driving the analytical, biological and functional characterization of proteins

Expertise in computational structure/function modeling of DNA/RNA binding proteins

Track record of modifying and optimizing protein function to improve key performance characteristics

Ability to work as part of a team with excellent communication skills

* Participants who complete a short wellness assessment qualify for FREE coverage in our HIP PPO medical plan. Free coverage applies in the next calendar year.

Learn more about our health and wellness benefits, which provide the security to help you and your family live full lives:

Follow your career aspirations to Abbott for diverse opportunities with a company that can help you build your future and live your best life. Abbott is an Equal Opportunity Employer, committed to employee diversity.

Connect with us at , on Facebook at and on Twitter @AbbottNews and @AbbottGlobal.

The base pay for this position is $(phone number removed) - $(phone number removed). In specific locations, the pay range may vary from the range posted.

Get job alerts

Create a job alert and receive personalized job recommendations straight to your inbox.

Create alert