Skip to main content

This job has expired

PhD Studentship - A chemical biology approach to identifying cyclic peptide protein degradors.

Employer
Global Academy Jobs
Location
United Kingdom
Closing date
Aug 31, 2019

Job Details

We are seeking a talented and motivated scientist to work on a 3.5 year interdisciplinary PhD project in the field of chemical biology. The project will be conducted in the Tavassoli lab at the School of Chemistry, University of Southampton.

The Tavassoli lab have pioneered methods for the generation and screening of cyclic peptide libraries. The approach, called SICLOPPS, has led to the identification and development of a number of first in class inhibitors; for a review see: https://www.sciencedirect.com/science/article/pii/S1367593116301818

The aim of this project is to use cyclic peptides discovered using SICLOPPS screening, in proteolysis targeting chimera molecules (PROTACs). PROTACs are a new and exciting class of therapeutic agents that promise to significantly impact drug discovery. This 3.5 year PhD project will combine the Tavassoli lab's expertise in identifying and developing cyclic peptide protein-protein interaction inhibitors with PROTAC development.

The ideal candidate will have prior lab-based experience of chemical biology and/or synthetic organic chemistry. However, this isn't essential, and appropriate training will be provided to the successful candidate as part of their PhD.

More information about the Tavassoli lab can be found on the University of Southampton website: https://www.southampton.ac.uk/chemistry/about/staff/ali1.page

Please feel free to contact Ali by email ali1(at)soton.ac.uk if you have any questions or would like to discuss the opportunity informally.

This 3.5 year studentship covers UK tuition fees and provides an annual tax-free stipend at the standard EPSRC rate, which is £15,009 for 2019/20.

Applicants must be UK or EU residents with no restrictions on how long they can stay in the UK and have lived here for at least 3 years prior to the start of the studentship. This residence cannot be mainly for the purpose of receiving full-time education.

For further guidance on funding, please contact feps-pgr-apply@soton.ac.uk

Company

Global Academy Jobs works with over 250 universities worldwide to promote academic mobility and international research collaboration. Global problems need international solutions. Our jobs board and emails reach the academics and researchers who can help.

"The globalisation of higher education continues apace, driving in turn the ongoing development of the global knowledge economy, striving for solutions to the world’s problems and educating a next generation of leaders and contributors."

Company info
Website

Get job alerts

Create a job alert and receive personalized job recommendations straight to your inbox.

Create alert