Postdoctoral position in Protein Biochemistry

Applications are invited for postdoctoral research to study the relationship between structure and function of specific molecular chaperones with emphasis in protein-protein and protein-ligand interactions. The goal is to build models to explain the mechanism by which molecular chaperones interact with unfolded substrates and transfer them to specified molecular machines. Our group seeks also to identify potential targets for therapeutic intervention.

The successful candidate will have a relevant Post-doc in Biochemistry or correlated areas and will have experience in the techniques involved, including molecular and cellular biology, protein purification, molecular biophysics, structural biology and protein-protein interaction.

Evidence of practical work experience in cell fluorescence microscopy, NMR, electronic microscopy and/or SAXS would be an advantage.

Project: Functional cellular study of the high molecular mass oligomers of the mortalin and the effects of mitochondrial cochaperones in their structure.

Location: São Carlos Institute of Chemistry, USP, São Carlos, SP, Brazil

Supervisor: Prof. Dr. Júlio César Borges

- Period: one to four years, depending on performance.

- Expected beginning in November 2019.

- Benefits: FAPESP fellowship (monthly stipend of R$ 7.373,10; expenditure on transport; aid installation; and research contingency funds). More information: http://www.fapesp.br/en/5427

- Main obligations: The candidate should have concluded a doctorate less than seven years before the beginning of the PD fellowship; The fellowship demands full time dedication to the research project; The fellowship holder may not hold any formal or informal employment nor receive, during the term of the fellowship. More information: http://www.fapesp.br/en/5427