Engineer position Droplet-based microfluidics/Single-cell

The position is offered in the frame of the ANR-funded Deindrop collaborative project that brings together the complementary expertise of the group of Andrew Griffiths and Deinove society in droplet-microfluidics and novel anti-infectious molecules studies. The successful candidate will join a highly multidisciplinary team, with experience spanning biology, chemistry and physics and also work in close contact with Deinove.

The throughput of droplet microfluidics coupled to next generation sequencing allows single-cell RNA sequencing of > 104 individual cells. Our goal is to is to implement an innovative droplet-based microfluidics approach in order to study novel anti-infectious molecules and the develop new generations of drugs capable of responding to the global challenge of antibiotic resistance.

The research activities of the Laboratory of Biochemistry at ESPCI Paris, directed by Prof. Andrew GRIFFITHS, are based around droplet-based microfluidics, a powerful new ultrahigh-throughput system in which reaction volumes can be miniaturized by up to a million-fold compared to conventional assays in microtiter plates. This opens up exciting prospects for the development of extremely innovative systems with many applications in the Life Sciences.

We are seeking a highly motivated engineer to work on single-cell droplet-based microfluidics and next generation sequencing. Requirements are a PhD in molecular biology and/or cellular biology and interest in learning how to use microfluidics systems. Flexibility, autonomy, the ability to work in a highly multidisciplinary team and in a highly interactive research consortium as well as good interpersonal skills are essential.